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Layoffs
Spruce Axes 55% of Staff, Leaving Shoestring Crew To Focus on New Rare Disease Asset
Spruce Biosciences is cutting over half of its employees as it looks to secure accelerated approval of a Sanfilippo syndrome therapy it recently acquired from BioMarin.
April 28, 2025
·
1 min read
·
Angela Gabriel
Layoff Tracker
Ono Cuts 83 Employees in Massachusetts
2024 was a tough year for the biopharma industry, with several companies cutting hundreds or even thousands of employees. Follow along as
BioSpace
tracks job cuts and restructuring initiatives throughout 2025.
April 28, 2025
·
181 min read
·
BioSpace Editorial Staff
Bladder cancer
Pfizer’s Subcutaneous PD-1 Cuts Risks in Bladder Cancer but Misses Survival Endpoint
Pfizer’s sasanlimab, when used with standard of care, reduced the likelihood of disease recurrence or progression, death due to any cause or persistence of cancer cells by 32% in patients with high-risk non-muscle invasive bladder cancer.
April 28, 2025
·
1 min read
·
Tristan Manalac
Press Releases
Medicus Pharma Ltd. Announces a Binding Letter of Intent to Acquire Antev Ltd. for ~US$75 Million in a Share Exchange Transaction
Antev Shareholders to Receive Aggregate ~19% Equity Stake in Medicus, Plus US$65 Million in Contingent Payments
April 28, 2025
·
10 min read
Press Releases
Moss Genomics Launches “Perennial” Genomics Platform, Closes on 130 ETH
April 28, 2025
·
7 min read
Press Releases
Theralase Discovers New Mechanism of Action of Lead Drug
Theralase(R) Has Discovered a New Mechanism of Action in Its War on Cancer; Specifically, Ruvidar’s(TM) Ability to Inhibit DeUbiquitinating Enzymes, an Important Class of Enzymes Which Have Been Linked to Numerous Cancers and Neurogenerative Diseases
April 28, 2025
·
7 min read
Press Releases
American Aires Announces Record Q4 and Annual 2024 Order Volume
April 28, 2025
·
18 min read
Bladder cancer
J&J Declares ‘Sustained Disease Control’ With Bladder Cancer Drug-Device Combo
The targeted drug release device TAR-200 shows promising response and disease-free survival rates in specific populations of patients with non-muscle-invasive bladder cancer.
April 28, 2025
·
2 min read
·
Tristan Manalac
Drug Development
AACR 2025 Tracker: GSK, Boehringer Ingelheim Kick Off Meeting With New Data
With the American Association for Cancer Research’s annual conference now underway, oncology researchers can expect potentially practice-changing data in head and neck and lung cancer and key updates on hot modalities.
April 28, 2025
·
2 min read
·
BioSpace Editorial Staff
Cancer
Perioperative Keytruda Cuts Risk of Negative Events by Over 25% in Head and Neck Cancer
The FDA is currently reviewing Merck’s sBLA for Keytruda in head and neck cancer, with a target action date of June 23.
April 28, 2025
·
1 min read
·
Tristan Manalac
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