Hamilton Robotics Introduces Automated DNA Sample Enrichment Solution Using Roche 454 REM e System

Reno, Nevada and Branford, Connecticut, USA – January 30, 2012 -- Hamilton Robotics announced today a new automated solution for DNA sample enrichment on the MICROLAB STARlet Liquid Handling Workstation. Integrating Roche’s REM e liquid handling system, the workflow solution enriches up to eight DNA samples for subsequent sequencing on the GS FLX System. The integrated system automates the multiple-step enrichment process, resulting in reduced variability, more consistent results and significant time savings.

The Hamilton solution for REM e integration replaces five hours of dedicated manual work with an automated, walkaway procedure. Five different REM e protocols are available as fully automated STARlet methods. Predefined hardware to accurately position the REM e Deck module and the REM e Tube Racks on the STARlet deck are included with the solution. The REM e module performs vortexing, vacuum filtration, magnetic bead capture and heating. All liquid transfer steps are handled by the 1000 µL independent pipetting channels of the STARlet system.

454 Life Sciences, a Roche Company and Hamilton Company will continue to collaborate in developing automation solutions for the benchtop GS Junior System using the STAR and NIMBUS line products. REM e integration on the Hamilton MICROLAB NIMBUS workstation will offer customers a compact and affordable robotic platform for the lower-throughput needs of GS Junior customers.

About Roche

Headquartered in Basel, Switzerland, Roche is a leader in research-focused healthcare with combined strengths in pharmaceuticals and diagnostics. Roche is the world’s largest biotech company with truly differentiated medicines in oncology, virology, inflammation, metabolism and CNS. Roche is also the world leader in in-vitro diagnostics, tissue-based cancer diagnostics and a pioneer in diabetes management. Roche’s personalised healthcare strategy aims at providing medicines and diagnostic tools that enable tangible improvements in the health, quality of life and survival of patients. In 2010, Roche had over 80,000 employees worldwide and invested over 9 billion Swiss francs in R&D. The Group posted sales of 47.5 billion Swiss francs. Genentech, United States, is a wholly owned member of the Roche Group. Roche has a majority stake in Chugai Pharmaceutical, Japan. For more information: www.roche.com.

About Hamilton Robotics

Hamilton is a leading worldwide supplier of precision liquid handling equipment, laboratory automation and storage systems, serving customers in academic and private research laboratories, pharmaceutical and clinical diagnostic companies and governmental institutions. Hamilton maintains headquarters in Reno, Nevada and Bonaduz, Switzerland, both of which house R&D and production facilities. Hamilton has subsidiaries for direct sales and service in many countries and works with a wide distributor network in other regions. Hamilton is a privately held company. For more information, visit www.hamiltonrobotics.com.

For life science research only. Not for use in diagnostic procedures.

454, 454 LIFE SCIENCES, 454 SEQUENCING, and GS FLX are trademarks of Roche.

All other product names and trademarks are the property of their respective owners.

For further information please contact:

Roche Diagnostics

Dr. Burkhard Ziebolz

Phone: +49 8856 604830

Email: burkhard.ziebolz@roche.com

Hamilton Robotics

Bobby Chavli

Phone: 775-858-3000 ext. 540

Email: bobby.chavli@hamiltoncompany.com

454 Life Sciences Corporation, a Roche Company

Katie Montgomery

Phone: 203-871-2300

Email: katie.montgomery@roche.com

Dahlgren Communications

Jennifer Dahlgren,

Phone: 530-265-0538

E-mail: dahlgrenpr@comcast.net

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