CHICAGO--(BUSINESS WIRE)--Abraxis BioScience, Inc. (NASDAQ:ABII), a fully integrated, global biotechnology company, today announced the presentation of results from an ongoing single-arm, open-label, Phase II clinical trial evaluating solvent-free ABRAXANE® for Injectable Suspension (paclitaxel protein-bound particles for injectable suspension) (albumin bound) in combination with trastuzumab and carboplatin for the first-line treatment of patients with HER2-positive metastatic breast cancer. The preliminary analysis showed that weekly ABRAXANE (ABI-007 or nab-paclitaxel) (100 mg/m2 three weeks on treatment, one week off) followed by carboplatin (AUC of 6 every four weeks) plus trastuzumab (4 mg/kg loading dose followed by 2 mg/kg on subsequent visits) demonstrated a 53 percent overall response rate and median progression free survival of nearly 16 months. The findings were presented today at the 44th Annual Meeting of the American Society of Clinical Oncology held May 30-June 3 in Chicago.
