Increasing efforts to accelerate immunization and implementation of TB control strategies in developing countries, rapidly rising prevalence of tuberculosis globally, and increasing use of BCG vaccine to treat superficial carcinoma of bladder are some key factors expected to drive market growth.
Increasing efforts to accelerate immunization and implementation of TB control strategies in developing countries, rapidly rising prevalence of tuberculosis globally, and increasing use of BCG vaccine to treat superficial carcinoma of bladder are some key factors expected to drive market growth
The global BCG vaccine market size is expected to reach USD 73.02 Million in 2028 at a CAGR of 4.5% during the forecast period, according to the latest report by Reports and Data. Rapid advancements in pediatric TB research and increasing vaccination of children to prevent severe childhood tuberculosis, increasing focus on using recombinant BCG strains to develop enhanced effectiveness of BCG vaccine, and rapidly rising demand for BCG vaccine from emerging economies to combat high prevalence of tuberculosis are major factors expected to drive market revenue growth over the forecast period. Over the recent past, extensive R&D activities have been carried out to explore potential use of BCG vaccine as an immune modulator in autoimmune diseases. This is another key factor expected to further contribute to revenue growth of the market going ahead.
Tuberculosis infection elicits a complex immunologic response, leading to unique host-pathogen interaction that makes it difficult to treat and control. The introduction of Bacillus Calmette-Guérin (BCG) revolutionized the treatment and prevention of tuberculosis. BCG is the most widely used vaccine worldwide, and over 100 million children across the globe are administered with BCG vaccine each year. In countries where tuberculosis is not prevalent, BCG vaccine is given to children at high risk. BCG vaccine is also effective against Buruli ulcer infection, other non-tuberculous mycobacteria infections, and in treatment of bladder cancer. Some strains of BCG vaccine reduce all-cause mortality by inducing protection against infections with non-related pathogens, and this has further led to increasing number of research and development activities to understand the molecular mechanisms of beneficial off-targets of BCG vaccine, which is expected to further drive market growth going ahead.
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BCG vaccination is a cost-effective interactive against tuberculosis, and several low- and lower-income countries have the necessary infrastructure for BCG vaccine procurement and administration. Many research studies have also highlighted the potential of BCG vaccine to confer cross-protective effects that can be explained through innate immune memory, which has further expanded its use in the treatment of respiratory infectious diseases and ongoing SARS-CoV-2 clinical trials. In certain situations, BCG vaccine can be used as a potential adjuvant to reduce severity of COVID-19 infection, and preliminary studies have suggested that BCG vaccination could enhance vaccine-induced immunity against COVID-19 virus, and this can further drive market growth going ahead. However, global shortage of BCG vaccines, inaccessibility to vaccines and advanced healthcare infrastructure due to poor socioeconomic conditions, and increasing number of clinical trials to develop vaccines to replace BCG vaccine in controlling the spread of tuberculosis are some key factors expected to restrain market growth over the forecast period.
Some Key Highlights from the Report:
- Immune BCG segment is expected to account for largest revenue share over the forecast period owing to increasing administration of BCG vaccine as a part of routine immunization schedule, growing awareness regarding cross protective effects of BCG vaccine, and growing focus on reducing prevalence of pulmonary tuberculosis and childhood mortality.
- Pediatric segment is expected to register significant revenue CAGR over the forecast period, attributable to increasing prevalence of childhood tuberculosis in developing countries, rising number of mandatory BCG vaccination programs, and research and advancements in pediatric TB research to boost effectiveness of BCG vaccine in children and new born babies.
- Hospital segment is expected to register significant revenue growth during 2021-2028, attributable to availability and priority access of hospitals to vaccine, implementation of TB control strategies in premises, availability of proper storage and handling conditions, and robust facilities and medical infrastructure.
- Asia Pacific is expected to dominate other regional markets in terms of revenue share over the forecast period, attributable to increasing demand for BCG vaccine to combat rising prevalence of tuberculosis and other mycobacterial infections in the region, emphasis on accelerating immunization in at-risk individuals, availability of high-quality of TB services in APAC countries, and growing number of strategic collaborations to boost TB control strategies in the region.
- Merck & Co., Inc., Sanofi Pasteur, Japan BCG Laboratory, China National Biotec Group, Serum Institute of India Pvt. Ltd., InterVax Ltd., GreenSignal Bio Pharma Limited (GSBPL), and Statens Serum Institut are some key companies in the global BCG vaccine market.
- In July 2021, Hackensack Meridian Center for Discovery and Innovation received a USD 6.4 million grant from NIH for accelerating research on new tuberculosis vaccine concept, wherein the team will improve efficacy of BCG by genetically engineering it to effectively stimulate B-cell development and survival.
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For the purpose of this report, Reports and Data has segmented the BCG vaccine market based on type, application, end use, and region:
Type Outlook (Revenue, USD Million; Volume, Tons; 2018-2028)
- Immune BCG
- Therapy BCG
Application Outlook (Revenue, USD Million; Volume, Tons; 2018-2028)
- Pediatric
- Adult
End-Use Outlook (Revenue, USD Million; Volume, Tons; 2018-2028)
- Hospitals
- Clinics
- Others
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Regional Outlook (Revenue, USD Million; Volume, Tons; 2018-2028)
- North America
- U.S.
- Canada
- Mexico
- Europe
- Germany
- U.K.
- France
- Italy
- BENELUX
- Rest of Europe
- Asia Pacific
- China
- India
- Japan
- South Korea
- Rest of APAC
- Latin America
- Brazil
- Rest of LATAM
- Middle East & Africa
- Saudi Arabia
- U.A.E.
- South Africa
- Rest of MEA
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