Cell-Free DNA (cfDNA) Testing Market Size to Reach USD 28.28 Billion in 2028 | Industry Trends – Increasing Prevalence of Chromosomal Disorders and Rising Number of Cell-Free DNA (Cfdna) Testing Procedures

According to Emergen Research, the global cell-free DNA (cfDNA) testing market size was USD 4.79 billion in 2020 and is expected to reach USD 28.28 billion in 2028 and register a revenue CAGR of 26.2% during the forecast period, 2021-2028.

Emergen Research has published its latest report titled “Cell-Free DNA (cfDNA) Testing Market, By Type (Cell-free fetal DNA, Circulating tumor DNA, Donor-derived cell-free DNA), By Technology (MPSS, t-MPS, SNP, Others), By Application (Transplantation, Gynecology, Oncology, Others), and By Region Forecast to 2028”

According to Emergen Research, the global cell-free DNA (cfDNA) testing market size was USD 4.79 billion in 2020 and is expected to reach USD 28.28 billion in 2028 and register a revenue CAGR of 26.2% during the forecast period, 2021-2028.

Market Dynamics:

The global cell-free DNA (cfDNA) testing market revenue growth is majorly attributed to factors such as rising prevalence of chromosomal abnormalities in infants, growing demand for low-risk obstetric procedures for prenatal testing, increasing prevalence of life-threatening diseases such as cancer, and increasing risks & complications associated with late pregnancies. Cell-free DNA comprises DNA fragments that circulate in the blood and act as significant biomarkers in the human body. Cell-free DNA tests are prenatal tests performed to detect various genetic disorders, which are caused by chromosomal abnormalities. However, these tests cannot detect of all types of chromosomal disorders. Cell-free DNA tests can also help in the detection of specific mutations in cancer patients.

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Increasing applications of these tests in gynecology, oncology, transplantation, and acute infectious diseases, growing preference for non-invasive DNA tests, rising awareness of maternal and fetal health, and increasing government investments in healthcare infrastructure development are some of the other major factors expected to boost the global market revenue growth over the forecast period. Market revenue growth, however, is hampered by factors such as rising costs of cfDNA tests, lack of skilled healthcare professionals – mainly in low-income countries – and ethical issues concerned with genetic testing in many parts of the world.

COVID-19 Impact Analysis:

  • Social distancing and restrictions severely disrupted businesses and operations
  • Lockdowns caused disruptions in transportation and logistics
  • Impacted manufacturing activities and mining operations globally
  • Took a toll on economy of various countries
  • Caused sudden and drastic downturn in economic activity
  • Disrupted agriculture, fisheries, dairy, and other sectors
  • Caused loss of employment and financial crisis
  • Supply impacts were further compounded owing to reduced disposable income
  • Emergence of variants continue to cause concerns and impact normal routines

Cell-free fetal DNA Segment Accounted for Largest Revenue Share in 2020:

Based on type, the global cell-free DNA (cfDNA) testing market is segmented into cell-free fetal DNA test, circulating tumor DNA test, and donor-derived cell-free DNA test. The cell-free fetal DNA test segment accounted for the largest revenue share in the global market in 2020. Cell-free fetal DNA testing is a non-invasive DNA testing procedure that involves no risks of problems such as CVS (chorionic villus sampling) or amniocentesis. Growing awareness of such benefits of the procedure is one of the key factors boosting revenue growth of this segment.

Gynecology Segment to Account for Fastest Revenue CAGR:

Based on application, the global cell-free DNA (cfDNA) testing market is segmented into transplantation, gynecology, oncology, and others. The gynecology segment is projected to register the fastest revenue growth rate in the global market over the forecast period. Increasing applications of cell-free DNA tests in gynecology, rising prevalence of genetic disorders in infants, and increasing risks of serious pregnancy complications are among the major factors expected to boost revenue growth of this segment.

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North America Accounted for Largest Revenue Share in 2020:

Among regional markets, the North America cell-free DNA (cfDNA) testing market accounted for the largest revenue share in the global market in 2020. Increasing prevalence of chromosomal disorders in infants, growing demand for non-invasive prenatal tests, technological advancements in DNA testing, and presence of highly advanced healthcare infrastructure and leading market players in the region, such as Illumina Inc., Quest Diagnostics, and Agilent Technologies, are major factors contributing to the North America market revenue growth.

Major Companies in the Global Cell-Free DNA (cfDNA) Testing Market Include:

  • CareDx, Inc.
  • Sequenom, Inc.
  • Illumina Inc.
  • Biocept, Inc.
  • Quest Diagnostics
  • Agilent Technologies, Inc.
  • Biodesix, Inc.
  • Guardant Health, Inc.
  • Allenex AB
  • Roche Holdings AG

For the purpose of this report, Emergen Research has segmented the global cell-free DNA (cfDNA) testing market on the basis of type, technology, application, and region:

Type Outlook (Revenue, USD Billion; 2018-2028)

  • Cell-free fetal DNA (NIPT) test
  • Donor-derived cell-free DNA test
  • Circulating tumor DNA test

Technology Outlook (Revenue, USD Billion; 2018-2028)

  • MPSS
  • t-MPS
  • SNP
  • Others

Application Outlook (Revenue, USD Billion; 2018-2028)

  • Transplantation
  • Gynecology
  • Oncology
  • Others

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Region Outlook (Revenue, USD Billion; 2018-2028)

  • North America
    • U.S.
    • Canada
    • Mexico
  • Europe
    • Germany
    • France
    • U.K.
    • Italy
    • Spain
    • BENELUX
    • Rest of Europe
  • Asia Pacific
    • China
    • India
    • Japan
    • South Korea
    • Rest of Asia Pacific
  • Latin America
    • Brazil
    • Rest of Latin America
  • Middle East & Africa
    • Saudi Arabia
    • U.A.E.
    • South Africa
    • Turkey
    • Rest of Middle East & Africa

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