Increasing application of chromatography experiments, rising demand for monoclonal antibodies, and rising R&D expenditure and investment are key factors driving market growth.
Increasing application of chromatography experiments, rising demand for monoclonal antibodies, and rising R&D expenditure and investment are key factors driving market growth
The global desalting and buffer exchange market size is expected to reach USD 1,691.9 Million by 2028 at a CAGR of 10.3%, according to the latest report by Reports and Data. Rapid progress in proteomics and genomics research, growing investment and R&D expenditure in biopharmaceutical sector, and increasing demand for monoclonal antibodies are key factors expected to drive market revenue growth over the forecast period. Growing applications of chromatography in chemicals industry and fast-paced advancements in molecular chemistry are some other key factors expected to drive revenue growth of the market going ahead.
Desalting and buffer exchange are vital processes used to separate large molecules from small molecules or restore the current buffer system with one that is more appropriate for specific downstream applications. These methods are based on gel filtration chromatography and both the methods aim to recover components of sample in buffers used. Desalting is primarily carried out to separate salts from protein solutions, phenol and unmixed nucleotides from nucleic acids, and excessive labeling agents from conjugated proteins. Buffer exchange is generally performed to transfer protein solution into a buffer system that is well-suited for downstream applications. Rapid advancements in materials and designs used to develop diafiltration, dialysis, and desalting devices according to the need of experiments is expected to support market revenue growth over the forecast period.
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Rising investment and R&D expenditure by pharmaceutical and biotechnology companies and growing global demand for monoclonal antibodies to develop more efficient therapeutic approaches are expected to drive market growth over the forecast period. However, lack of skilled professionals, low awareness about these methods, and high costs associated with reagent and equipment are factors expected to hamper market growth to a certain extent over the forecast period.
Some Key Highlights From the Report:
- Kits segment is expected to account for a significantly large share in the market in terms of revenue over the forecast period owing to increasing application of desalting kits in preparation of analytical and concentrated protein samples.
- Filtration segment is expected to register rapid revenue CAGR over the forecast period owing to increasing use of ultrafiltration in monoclonal antibody production, growing need to reduce production costs, and rising number of benefits offered by ultrafiltration as compared to other techniques.
- Bioprocess segment is expected to register considerable revenue growth over the forecast period owing to increasing research and development in the bioprocessing field and growing production of monoclonal antibodies.
- North America is expected to account for largest share in the global market in terms of revenue over the forecast period owing to increasing R&D activities, growing demand for biologics, and increasing focus on genomics and proteomics research. In addition, robust presence of key manufacturers in the region is expected to support market growth.
- Major companies in the global market include Thermo Fisher Scientific, Inc., Merck AG, GE Healthcare, Danaher Corporation, Sartorius, Agilent Technologies, Inc., VWR International LLC, Bio-works Technologies AB, Bio-Rad Laboratories, and Norgen Biotek Corp.
- In April 2020, Pall Corporation introduced the next-generation of its lab-scale tangential flow filtration (TFF) system. The Minimate EVO TFF system is user-friendly and designed to streamline lab-scale concentration, desalting, and buffer exchange workflows.
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For the purpose of this report, Reports and Data has segmented the global desalting and buffer exchange market based on product, technique, application, and region:
Product Outlook (Revenue, USD Million; 2018-2028)
- Kits
- Cassettes & Cartridges
- Spin Columns
- Others
Technique Outlook (Revenue, USD Million; 2018-2028)
- Filtration
- Ultrafiltration
- Dialysis
- Chromatography
- Size Exclusion Chromatography
- Other Chromatography Techniques
- Precipitation
Application Outlook (Revenue, USD Million; 2018-2028)
- Bioprocess Application
- Diagnostic Application
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Regional Outlook (Revenue, USD Million; 2018-2028)
- North America
- U.S.
- Canada
- Mexico
- Europe
- Germany
- U.K.
- Italy
- France
- BENELUX
- Rest of Europe
- Asia Pacific
- China
- India
- Japan
- South Korea
- Rest of APAC
- Latin America
- Brazil
- Rest of LATAM
- Middle East & Africa
- Saudi Arabia
- U.A.E.
- South Africa
- Rest of MEA
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