Advent of the chemical modification process to increase the nuclease resistance of aptamers, and, in turn, enhance their therapeutic properties creates opportunities galore for players in the aptamer market.
Advent of the chemical modification process to increase the nuclease resistance of aptamers, and, in turn, enhance their therapeutic properties creates opportunities galore for players in the aptamer market. This has also lead to steady increase in the demand for aptamers and related products from research institutions. Ongoing research & development activities have led to the adoption of aptamers, both, as drugs and drug-carriers, and their application as diagnostics tools is opening new growth avenues for manufacturers.
In future, the application of aptamers will meet an expanded scope in the food and beverage industry as biosensors to ensure the quality of products. On the back of such favourable factors, a recently published study by Fact.MR opines that, the aptamer market would progress at an impressive pace, at a CAGR of 21% during the forecast period (2020-2025).
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Lack of Proper Information May Impede Market Growth
There are factors that will drive the growth of the global market in the coming years of the forecast period. Continuous advancements in selection technique remain a critical lever to the growth of the aptamer market. The conventional Systemic Evolution of Ligands by Exponential Enrichment (SELEX) technique included lengthy iterative steps, which would delay probe selection and further slowdown the selection process.
“Unlike other drugs and diagnostic tools, aptamers lack a standard regulatory standard for quality and safety. However, the approval process remains highly stringent in developed regions such as North America and Europe. On the backdrop of lack of universal regulatory norms, the penetration of aptamers in these regions is projected to remain limited to some extent,” finds Fact.MR
Being a relatively novel technology, some characteristics of aptamers are still unexplored, which poses a technical challenge for manufacturers. Low molecular weight of these molecules causes rapid degradation of biological media and blood, which needs proper synthesis to keep unwanted characteristics of aptamers in check. However, manufacturers choose to avoid using these molecules, on the backdrop of lack of knowledge regarding aptamers and lack of technical expertise. Moreover, aptamers are found to have a short half-life (within the range of minutes to hours), which impedes the practical application of these molecules in the development of therapeutics.
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Presence of High-Tech Healthcare Infrastructure to Push North America Region Growth
North America’s dominance in the aptamer market is driven by the early-bird’s advantage of advanced technology that companies are receiving in the region. Constant progress in the field of research & development of therapeutics and diagnostics equipment is projected to demand an ongoing supply of aptamers. Thus, this is expected to creating opportunities for companies operating in the North American aptamer market space.
In Europe, there has been a marked spike in awareness regarding health issues, which is imparting strength to the demand for effective diagnostic tools to detect infectious and chronic diseases. This will create opportunities for the aptamer market in Europe from the biotechnology industry.
“Growth of the aptamer market in Asia Pacific is projected to remain significantly driven by collaborative efforts taken by players in developed regions to foray into the untapped market,” notes Fact.MR Knowledge sharing of technologies and pharmaceutical know-hows among established players of North America and Europe and prominent/local players of Asia Pacific is projected to pave way for expansion of the aptamer market during the forecast period.
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