Extensive R&D activities to develop niacinamide therapies for treatment of cancer and rising preference for OTC cosmeceuticals are expected to drive market revenue growth.
Extensive R&D activities to develop niacinamide therapies for treatment of cancer and rising preference for OTC cosmeceuticals are expected to drive market revenue growth
The global niacinamide market size is expected to reach USD 785.02 Million in 2028 at a CAGR of 2.6% during the forecast period, according to the latest report by Reports and Data. Increasing use of niacinamide in anti-acne topical formulation, availability of cost-effective niacinamide oral drugs, growing number of clinical trials to study the efficacy of niacinamide in lowering caseload of non-melanoma skin cancers, and enhanced safety and tolerability of niacinamide are key factors expected to drive market revenue growth over the forecast period. Niacinamide-containing serums and moisturizers effectively treat atopic dermatitis by reducing transepidermal water loss and increasing the level of free fatty acids.
Niacinamide is the amide form of water-soluble vitamin B3 and is primarily involved in DNA repair, cellular energy metabolism, regulating levels of NAD, as well as transcription process. Niacinamide is a robust immunosuppressant and is widely used to treat skin diseases such as discoid lupus erythematosus, and bullous pemphigoid. Niacinamide inhibits production of inflammatory cytokines such as IL-1β, IL-6, IL-08, and TNF, replenishes cellular energy, as well as prevents over activation of PARP-1 gene – which plays a crucial role in cell senescence, ageing, and cancer. Niacinamide is also extensively studied to understand and assess its role in the prevention of non-melanoma and other types of skin cancers. In addition, it prevents photocarcinogenesis, boosts collagen production, and smoothens wrinkles and fine lines on aging skin. Niacinamide supplements are also used in wound healing, treating psoriasis, and improving pigmentation disorders, which, in turn, is expected to further boost revenue growth of the market.
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Niacinamide readily penetrates skin surface in humans and increases levels of NADH in cutaneous tissues when applied topically. Topical application of niacinamide has many clinical benefits such as it reduces skin redness, lightens hyperpigmentation, and improves sallowness. Niacinamide elevates levels of NADPH, which is an important cofactor for fatty acid and lipid synthesis, and in turn, enhances skin barrier lipids and barrier function. It also reduces sebum production significantly, which makes it an excellent choice for people aiming for rejuvenated and wrinkle-free skin. These key factors are driving demand for cosmeceuticals containing niacinamide and are expected to continue to support market growth in the near future. However, side effects associated with oral ingestion, as well as topical application of niacinamide, such as upset stomach, nausea, gas, itchy and burning sensation on skin, and allergic responses can restrain market growth to a certain extent over the forecast period.
Some Key Highlights from the Report:
- Feed grade segment is expected to register a steady revenue share over the forecast period, attributable to increasing niacinamide supplementation in animal feed to boost absorption of other nutrients, improve weight gain, optimize food intake, enhance productivity, prevent vitamin B3 deficiency, and enhance overall health of livestock.
- Powder segment is expected to account for a large revenue share in the global market over the forecast period, owing to increasing use of niacinamide powder in food products and beverages, bakery mixes, nutritional powders, and cereals, among others. Niacinamide powder can also be mixed with non-conflicting treatments for application on face and skin for whitening, reducing pore and acne, and ant-ageing purposes.
- Pharmaceutical segment is expected to register a robust revenue CAGR over the forecast period, attributable to growing focus on development of niacinamide-based treatments for autoimmune skin diseases and other dermatological disorders, prevention of vitamin B3 deficiency, treatment of skin cancer, and inflammatory diseases in humans and animal models.
- Asia Pacific is expected to register a robust revenue CAGR over the forecast period, attributable to increasing demand for cosmeceuticals due to rising disposable income of people, access to a wide range of over-the-counter oral and topical medications, rising expenditure to develop advanced healthcare facilities, and presence of major pharmaceutical companies in the region.
- Some major companies profiled in the market report are Lonza Group, Vertellus, Vanetta, Zhejiang Lanbo Biotechnology, Foodchem International Corporation, Merck KGaA, Koninklijke DSM N.V., Bactolac Pharmaceutical Inc., BASF SE, and Lasons India.
- In October 2021, TRI-K Industries, Inc., which is a leading manufacturer and supplier of active ingredients to the personal care industry, introduced a new ingredient called Fision GlowPlex. It is a niacinamide-peptide complex for skin glow and it uses peptide technology of TRI-K that combines peptides with niacinamide, and is the first-of-its-kind active product for skin glow.
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For the purpose of this report, Reports and Data has segmented niacinamide market based on grade, form, end-use, and region:
Grade Outlook (Volume, Kilo Tons; Revenue, USD Million, 2018-2028)
- Pharmaceutical Grade
- Feed Grade
Form Outlook (Volume, Kilo Tons; Revenue, USD Million, 2018-2028)
- Granular
- Powder
- Liquid
End-Use Outlook (Volume, Kilo Tons; Revenue, USD Million, 2018-2028)
- Pharmaceutical
- Cosmeceutical
- Human Nutrition
- Animal Nutrition
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Regional Outlook (Volume, Kilo Tons; Revenue, USD Million, 2018-2028)
- North America
- U.S.
- Canada
- Mexico
- Europe
- Germany
- U.K.
- France
- Italy
- BENELUX
- Rest of Europe
- Asia Pacific
- China
- India
- Japan
- South Korea
- Rest of APAC
- Latin America
- Brazil
- Rest of LATAM
- Middle East & Africa
- Saudi Arabia
- U.A.E.
- South Africa
- Rest of MEA
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Some points on how the report benefits stakeholders:
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- Revenue break-up is provided for each segment in these formats for global, regional, and for each country in the respective region for each year between 2018 and 2028.
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