Continuous advances in medical technology and growing need for advanced physiological models are among the major factors boosting the global Organs-on-Chips (OOCs) market revenue growth.
Continuous advances in medical technology and growing need for advanced physiological models are among the major factors boosting the global Organs-on-Chips (OOCs) market revenue growth.
According to Emergen Research, the global organs-on-chips market size was USD 27.5 million in 2020 and is expected to reach USD 209.4 million in 2028 and register a revenue CAGR of 28.1% during the forecast period, 2021-2028.
Market Dynamics:
The global organs-on-chips market revenue growth is primarily attributed to factors such as increasing incidences of road accidents and severe physical injuries, rising volumes of surgical procedures, increasing applications of organs-on-chips in organ transplants, rising problems such as shortages in organ supply, and rising focus on disease modeling and developing animal model substitutes. Increasing R&D collaborations between leading pharmaceutical and biotechnology companies and organ-on-chip manufacturers, development of advanced bioartificial organs, growing focus of biotechnological companies on development of COVID-19 disease models to study novel drug compounds, and regulatory approvals for new product launches are other key factors expected to contribute to the global market revenue growth over the forecast period.
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Organs-on-chips (OOCs) are micro-scale systems that imitate the human body environment and are used in development of human tissue models for new drug testing and disease modeling. These systems are designed to recreate the natural physiology of the cells in the human body, and they contain tiny fluidic channels that reproduce air flow or blood, similarly as the human body. The transparency of these chips allows researchers to clearly see the functionality, response, and behavior of the organs at the molecular level. Hence, organs-on-chips act as a microenvironment to help researchers view and analyze the cellular activities that control different organ functions. Key applications of organs-on-chips include organ repair & regeneration procedures, in-vitro novel therapeutic target identification, new drug discovery & development, personalized medicine, molecular biology, disease modelling, physiological model development, and toxicology research.
COVID-19 Impact Analysis:
- Social distancing and restrictions severely disrupted businesses and operations
- Lockdowns caused disruptions in transportation and logistics
- Impacted manufacturing activities and mining operations globally
- Took a toll on economy of various countries
- Caused sudden and drastic downturn in economic activity
- Disrupted agriculture, fisheries, dairy, and other sectors
- Caused loss of employment and financial crisis
- Supply impacts were further compounded owing to reduced disposable income
- Emergence of variants continue to cause concerns and impact normal routines
Heart-on-Chip Segment Accounted for Largest Revenue Share in 2020:
The heart-on-chip segment accounted for the largest revenue share in the global market in 2020. key factors driving revenue growth of this segment are rising geriatric population, increasing prevalence of cardiovascular diseases (CVDs) across the globe, growing use of heart-on-chip in cardiovascular surgeries, and increasing applications of the microphysiological heart-on-chip in areas including in-vitro cardiac tissue bionic research, cardiovascular disease studies, cardiotoxicity testing, tissue regeneration, and development of personalized medicine.
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Physiological Model Development Segment to Account for Fastest Revenue CAGR:
The physiological model development segment is expected to register the fastest revenue CAGR in the global market over the forecast period. Increasing use of organs-on-chips in developing physiological microenvironments and growing demand for the product due to its advantages such as miniaturized scale, accurate control, and high cost-effectiveness are among the key factors contributing to revenue growth of this segment.
North America Market Accounted for Largest Revenue Share in 2020:
The North America organs-on-chips market dominated other regional markets in terms of revenue share in the global market in 2020. Major factors providing impetus to the North America market revenue growth are rising burden of chronic and acute diseases, rising cases of fatal road accidents and physical injuries, increasing volumes of organ transplant procedures, and growing demand for organs-on-chips for applications in organ repair & regeneration, new drug development, disease modelling, and physiological model development. Other factors boosting the regional market revenue growth are increasing R&D collaborations and new product launches and presence of state-of-the-art healthcare infrastructure and leading companies such as Nortis Inc., Emulate Inc., and AxoSim Inc. in the region.
Major Companies in the Global Organs-on-Chips Market Include:
- MIMETAS BV
- SynVivo Inc.
- Emulate Inc.
- InSphero AG
- CN Bio
- Nortis Inc.
- Organovo Holdings Inc.
- TissUse GmbH
- AxoSim Inc.
- Kirkstall Ltd.
Scope of Organs-on-Chips Research
| Report Details | Outcome |
| Market size in 2020 | USD 27.5 Million |
| CAGR (2021–2028) | 28.1% |
| Revenue forecast in 2028 | USD 209.4 Million |
| Base year for estimation | 2020 |
| Historical data | 2017–2019 |
| Forecast period | 2021–2028 |
| Quantitative units | Revenue in USD Million and CAGR in % from 2021 to 2028 |
| Report coverage | Revenue forecast, company ranking, competitive landscape, growth factors, and trends |
| Segments covered | Type, application, end-use, and region |
| Regional scope | North America; Europe; Asia Pacific; Latin America; Middle East & Africa |
| Country scope | U.S., Canada, Mexico, Germany, UK, France, Italy, Spain, Sweden, BENELUX, China, India, Japan, South Korea, Brazil, Saudi Arabia, UAE, South Africa, Israel |
| Key companies profiled | MIMETAS BV, SynVivo Inc., Emulate Inc., InSphero AG, CN Bio, Nortis Inc., Organovo Holdings Inc., TissUse GmbH, AxoSim Inc., and Kirkstall Ltd. |
| Customization scope | 10 hours of free customization and expert consultation |
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For the purpose of this report, Emergen Research has segmented the global organs-on-chips market based on type, application, end-use, and region:
Type Outlook (Revenue, USD Million; 2018-2028)
- Lung-On-Chip
- Heart-on-Chip
- Liver-on-Chip
- Intestine-on-Chip
- Kidney-on-Chip
- Skin-on-Chip
- Blood-brain-barrier-on-Chip
- Multiple-organs-on-Chip
- Others
Application Outlook (Revenue, USD Million; 2018-2028)
- Toxicology Research
- Drug Discovery
- Physiological Model Development
- Molecular Biology
- Disease Modelling
- Food Safety
- Others
End-use Outlook (Revenue, USD Million; 2018-2028)
- Pharmaceutical and Biotechnology Companies
- Research Institutes
- Personal Care Industry
- Others
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Region Outlook (Revenue, USD Million; 2018-2028)
- North America
- U.S.
- Canada
- Mexico
- Europe
- Germany
- France
- U.K.
- Italy
- Spain
- BENELUX
- Rest of Europe
- Asia Pacific
- China
- India
- Japan
- South Korea
- Rest of Asia Pacific
- Latin America
- Brazil
- Rest of Latin America
- Middle East & Africa
- Saudi Arabia
- U.A.E.
- South Africa
- Turkey
- Rest of Middle East & Africa
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