“Replace bogus PCR tests to avoid unnecessary Coronavirus lockdowns,” Urges Milford Molecular Diagnostics Director Dr. Sin Hang Lee

MILFORD, Conn.--(BUSINESS WIRE)-- The current Coronavirus chaos is largely caused by phony PCR tests marketed as RT-qPCR assays, explained Dr. Sin Hang Lee, director of Milford, Connecticut-based Milford Molecular Diagnostics (www.dnalymetest.com), in an article titled “qPCR is not PCR, Just as a Straightjacket is not a Jacket - The Truth Revealed by SARS-CoV-2 False-Positive Test Results.” https://researchinfotext.com/article-details/qPCR-is-not-PCR-Just-as-a-Straightjacket-is-not-a-Jacket-the-Truth-Revealed-by-SARS-CoV-2-False-Positive-Test-Results (the Article).

Now, even the general public is aware that RT-qPCR assays are generating numerable false-positive and false-negative test results, he said.

“Big Bio-Tech has used these questionable test results to move the goalposts arbitrarily in defining COVID-19 infections for statistics to cover up various business agendas at the expense of public interest,” said Dr. Lee.

Media reports have demonstrated that uninfected nursing home residents who tested false-positive have often been isolated in the same rooms with COVID-19 patients. This practice has led to fatal outcomes https://ctmirror.org/2020/07/23/one-patient-falsely-classified-by-ct-as-covid-19-positive-later-died/ .

“The entire population and economy have suffered from unnecessary lockdowns due to false-positive RT-qPCR test results. Both false-positive and false-negative RT-qPCR test results contributed to the current Coronavirus pandemic,” said Dr. Lee.

Unlike the current pandemic, when the SARS-1 was discovered in Asia in February 2003, the U.S. Centers for Disease Control and Prevention (CDC) immediately began its DNA sequencing work and published a set of SARS-CoV specific primers for performing genuine RT-PCR followed by DNA sequencing of a 348-bp amplified product for accurate diagnosis https://www.who.int/csr/sars/CDCprimers.pdf?ua=1 . The World Health Organization (WHO) also issued advice on how to use the recommended PCR primers for accurate detection of SARS virus RNA sequences https://www.who.int/csr/sars/primers/en/.

Neither the WHO nor the CDC promoted RT-qPCR as SARS-1 diagnostics in 2003. With accurate laboratory diagnosis of infected cases for timely isolation, SARS-1 was quickly under control with only 774 deaths worldwide. With quick isolation of properly identified infected cases, the SARS-1 virus had no chance to mutate, as Dr. Lee compared the two SARS outbreaks.

In the article, Dr. Lee reiterated that qPCR, which is really a hybridization assay, not PCR, and which is also used for human papillomavirus (HPV) diagnostics, has been known to have “built-in false positives” as other hybridization-based tests do. These false-positive HPV test results have been used knowingly to triage thousands of healthy women to needless colposcopic biopsies every year. The iatrogenic harms induced by these unnecessary invasive uterine cervical biopsies have been conveniently explained away by statistics since fatalities associated with cervical biopsies are rare. “But the exceptionally high death tolls among nursing home residents associated with false-positive SARS-CoV-2 RT-qPCR test results are hard to gloss over,” Dr. Lee wrote in the article.

In recounting Big Bio-Tech’s censorship of scientific discussions, Dr. Lee explained that the article was rejected immediately after initial submission, first, by the editor in chief of the International Journal of Molecular Sciences, then, a second time, by the editorial board of the International Journal of Geriatrics and Rehabilitation after the manuscript had already been accepted for publication following two favorable external peer reviews. It was finally published in a third journal after, yet, another round of peer review, he said.

On March 22, 2020 Dr. Lee sent an open letter to Dr. Anthony Fauci (https://justthenews.com/sites/default/files/2021-03/Letter%20to%20WHO%20and%20Dr.%20Fauci.pdf), alerting the U.S. government of the flaws of RT-qPCR tests which have been used as the basis for creating public policies in managing the COVID-19 outbreak. In his letter Dr. Lee proposed using RT-PCR followed by DNA sequencing as was recommended by the U.S. CDC for SARS-1 in 2003. The letter was ignored.

Now, the U.S. CDC has officially stated, “NAATs for SARS-CoV-2 specifically identify the RNA (ribonucleic acid) sequences that comprise the genetic material of the virus” https://www.cdc.gov/coronavirus/2019-ncov/lab/naats.html?ACSTrackingID=USCDC_2146-DM53226&ACSTrackingLabel=Laboratory%20Advisory%3A%20CDC%20Publishes%20New%20Web%20Page%20on%20Nucleic%20Acid%20Amplification%20Tests&deliveryName=USCDC_2146-DM53226.

The European CDC also stated, “Sequencing of (partial) genes and whole genomes (WGS) has been proven as a powerful method to investigate viral pathogen genomes, understand outbreak transmission dynamics and spill-over events and screen for mutations that potentially have an impact on transmissibility, pathogenicity, and/or countermeasures (e.g. diagnostics, antiviral drugs and vaccines). The results are key to informing outbreak control decisions in public health” https://www.ecdc.europa.eu/sites/default/files/documents/Sequencing-of-SARS-CoV-2-first-update.pdf.

To prevent unnecessary lockdowns as businesses start to reopen, Dr. Lee urges that all presumptive PCR-positive SARS-CoV-2 samples be sequenced for verification of the test results and for detection of variants of concern https://www.businesswire.com/news/home/20210505005306/en/First-of-its-kind-SARS-CoV-2-detection-by-partial-N-gene-sequencing-now-publicly-available-at-CLIA-Certified-Milford-Connecticut-laboratory.

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