According to latest report, the global cancer biologics market size was USD 103.98 billion in 2023, calculated at USD 111.40 billion in 2024, and is expected to reach around USD 207.24 billion by 2033, expanding at a CAGR of 7.14% from 2024 to 2033.
According to latest report, the global cancer biologics market size was USD 103.98 billion in 2023, calculated at USD 111.40 billion in 2024, and is expected to reach around USD 207.24 billion by 2033, expanding at a CAGR of 7.14% from 2024 to 2033.
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Biological therapy, also known as biotherapy or immunotherapy, has become a pivotal growth driver in the cancer biological therapy market by leveraging the body’s natural immune system to combat diseases such as cancer. This innovative approach provides targeted treatments that significantly enhance the body’s ability to fight disease. Designed to repair, stimulate, or enhance the immune response with precision, biological therapy addresses many limitations of conventional cancer treatments like surgery, radiation, and chemotherapy. While surgery and radiotherapy are effective for localized tumors, they fall short in treating disseminated disease or tumors in difficult-to-reach or dangerous locations. This gap underscores the rising demand for cancer biologics, fueling market growth by offering more effective and targeted treatment options.
The cancer biologics market is experiencing rapid growth, driven by the unique ability of biologic therapies to harness the body’s own power to combat cancer. These therapies utilize the immune system to eliminate cancer cells or reduce treatment side effects, thereby improving the body’s response to cancer in various ways: eliminating conditions that allow uncontrolled cell growth, helping the immune system halt the proliferation of cancer cells, making cancer cells easier for immune cells to destroy, promoting normal cell growth to prevent spread, blocking the transformation of normal cells into cancer cells, repairing normal cells damaged by chemotherapy or radiation, and preventing cancer from metastasizing. Created from living organisms through biological processes, biologics have extensive applications in oncology. As cancer often results from immune system malfunctions, biologic therapy can effectively repair, stimulate, or enhance immune responses. While traditional cancer treatments, such as surgery, radiation, and chemotherapy, have significant limitations, biologics provide targeted cancer treatment and can synergistically enhance chemotherapy outcomes. Utilizing biologics before the immune system is compromised offers a strategic advantage, highlighting their critical role in the evolving landscape of oncology treatments and driving significant market growth.
- In January 2024, Johnson & Johnson announced the acquisition of Ambrx, advancing next-generation antibody drug conjugates to transform cancer treatment.
- In March 2024, AstraZeneca acquired Fusion to accelerate the development of next-generation radioconjugates for cancer treatment.
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Cancer Biologics Market Dynamics
Driver
Biologics Revolutionizing Cancer Treatment
Biologics have long been integral to medical treatment, particularly in oncology, where they are deployed in various strategies. Immunotherapy, a prominent approach, harnesses the body’s immune system to combat cancer cells effectively. Other biologics are designed to inhibit tumor growth and aid recovery from anti-cancer treatments. Their ability to target specific aspects of cancer cells makes biologic therapies pivotal in cancer treatment. Monoclonal antibodies exemplify this complexity by targeting cancer cells and enhancing immune-mediated destruction. These advancements are driving substantial growth in the cancer biologics market, emphasizing their transformative impact on oncological care.
- In April 2024, AGC Biologics announced the successful completion of production of cancer-specific therapeutic antibody fragments with Var2 Pharmaceuticals.
- In June 2023, the FDA launched a pilot program to help reduce risks associated with using laboratory developed tests to identify cancer biomarkers.
Restraint
Challenges in Targeting Heterogeneous Cancer
The complexity of cancer presents significant challenges for advancing biological therapies. Each patient’s cancer exhibits unique characteristics, including variations within tumors and changes over time, complicating effective targeting with biologic treatments. The dynamic progression of cancer requires personalized therapeutic approaches tailored to individual patient profiles. These complexities hinder achieving consistent therapeutic efficacy across diverse cancer types and stages, thereby restraining the growth potential of the cancer biologics market.
Opportunity
Expanding Horizons in Cancer Biologics
Biologic drugs represent a frontier in medical research, revolutionizing cancer treatment and offering newfound hope to previously untreatable patients. Advances in molecular and cellular biology, coupled with technological innovations, are driving this transformation in biologics. A key advantage lies in their ability to target traditionally ‘undruggable’ targets that small-molecule therapies cannot reach. Their larger size, biologic therapies offer enhanced specificity and affinity for specific targets, thereby improving efficacy while minimizing off-target toxicity. This capability not only enhances treatment outcomes but also underscores significant opportunities for growth in the cancer biologics market.
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Report Highlights
By Drug Class Insights
The monoclonal antibodies segment has emerged as the dominant force in the cancer biologics market. Monoclonal antibodies, a type of targeted cancer therapy, are specifically designed to interact with particular targets on cancer cells, enhancing treatment precision and efficacy. Many monoclonal antibodies function as immunotherapy agents, aiding the immune system in attacking cancer. Naturally produced by the body, antibodies help the immune system identify and mark disease-causing germs, such as bacteria and viruses, for destruction. This dual role in targeted therapy and immunotherapy underscores the significant impact of monoclonal antibodies in advancing cancer treatment and solidifies their leading position in the market.
The cancer growth inhibitors segment is projected to achieve the highest CAGR in the cancer biologics market by application during the forecast period. As a type of targeted cancer drug, cancer growth inhibitors function by blocking the growth factors that the body produces to control cell growth. By inhibiting these growth factors, cancer growth inhibitors prevent cancer cells from dividing and proliferating. This targeted approach not only enhances the precision and effectiveness of cancer treatment but also positions cancer growth inhibitors as a crucial and rapidly expanding segment within the cancer biologics market.
By Application Insights
The blood cancer segment has emerged as the dominant application in the cancer biologics market. Blood cancer, which affects blood cells, includes common types such as leukemia, lymphoma, and myeloma, as well as myeloproliferative neoplasms (MPNs) and myelodysplastic syndromes (MDS). These cancers are caused by mutations in the DNA within blood cells, leading to abnormal cell behavior. These genetic changes typically occur during a person’s lifetime and are generally beyond their control. The high prevalence and complexity of blood cancers drive the significant demand for biologic therapies, solidifying this segment’s leading position in the market.
The lung cancer segment is poised to achieve the highest compound annual growth rate (CAGR) in the cancer biologics market by appl
