DIMERx Secures Global Rights to a Novel Amino Acid Prodrug Dimer Developed at Massachusetts General Hospital

• Company to Pursue Applications in Rare Diseases and Proprietary Medical Food Domains
• Deal Unlocks Opportunities for Future Collaborations

SAN FRANCISCO--(BUSINESS WIRE)-- DIMERx, Inc., an advance-stage biopharmaceutical company, announced today that it has secured rights from Massachusetts General Hospital (MGH) for a novel amino acid dimer to be developed for two rare disease indications in the U.S. and as a proprietary medical food for ex-U.S. markets. This exclusive patent license agreement marks a pivotal step in harnessing the therapeutic potential of amino acids as drugs. Through this strategic collaboration, DIMERx aims to challenge treatment paradigms across multiple health conditions.

The dimer, developed and patented by Maurizio Fava, M.D., Chair of Psychiatry at MGH, and by Xudong Huang, Ph.D., Co-Director of the Neurochemistry Lab of the MGH Department of Psychiatry, presents vast therapeutical potential and the company is excited to bring the groundbreaking molecule to patients. “I am delighted that DIMERx and MGH have entered into this agreement,” stated Dr. Fava. “DIMERx has been on the forefront of harnessing therapeutic potential of compounds with covalent bonds through dimerization. The company has a strong scientific foundation within the small molecule modality and has visionary leadership. DIMERx is the right partner, and we are looking forward to advancing the dimer from paper to patients.”

Co-founders Nikhilesh Singh, M.Pharm., Ph.D., Chief Executive Officer, and Gregory Beyer, Chief Financial Officer of DIMERx, expressed enthusiasm about the transformative potential of the compound. Dr. Singh stated, “This significant milestone marks a pivotal moment for DIMERx, and we are incredibly grateful to Dr. Fava for the opportunity to collaborate with him and one of the premier research institutes in the world.”

About DIMERx, Inc.

DIMERx is a clinical-stage biopharmaceutical company focused on the development of a novel platform of first-in-class dimer therapeutics. The company’s lead asset, DMX-101, has demonstrated safety, tolerability, and effectiveness in controlling abdominal pain and GI motility in a Phase 2 study. DIMERx is currently evaluating financing options that align with the company’s vision of establishing itself as a transformative drug company within the small molecule dimer space.

Forward-Looking Statements

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