Whole Exome Sequencing Market Trend – Increasing Demand for Personalized Medicine

Increasing investments in research and development activities, rapid advancements in next-generation sequencing techniques, and growing awareness about exome sequencing technology are some key factors expected to drive global market growth.

Increasing investments in research and development activities, rapid advancements in next-generation sequencing techniques, and growing awareness about exome sequencing technology are some key factors expected to drive global market growth

Market Dynamics:

Whole exome sequencing is a genomic technique widely used for sequencing the protein-coding regions of genome. Whole exome sequencing can efficiently identify coding variants and is used for a broad range of applications including genetic disease, population genetics, and cancer studies. It is rapidly gaining traction owing to increasing prevalence of genetic disorders and rare diseases, rapid advancements in sequencing techniques, and low costs associated with exome sequencing as compared to whole genome sequencing.

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Factors such as increasing inclination towards next-generation sequencing methods for identifying, treating, and monitoring chronic diseases, rising investments in research-based projects, growing alliances among leading companies and research centers for drug discovery are expected to drive global market revenue growth. In addition, availability of latest kits, software, and systems for exome sequencing, and ongoing research activities on rare diseases are other factors expected to fuel global market growth during the forecast period. However, ethical and legal issues about genome extraction, dearth of skilled professionals for handling these systems, and lack of funds and grants for research in many countries across the globe are some key factors that can restrain market growth during the forecast period.

COVID-19 Impact Analysis

  • Social distancing and restrictions severely disrupted businesses and operations
  • Lockdowns caused disruptions in transportation and logistics
  • Impacted manufacturing activities and mining operations globally
  • Took a toll on economy of various countries
  • Caused sudden and drastic downturn in economic activity
  • Disrupted agriculture, fisheries, dairy, and other sectors
  • Caused loss of employment and financial crisis
  • Supply impacts were further compounded owing to reduced disposable income
  • Emergence of variants continue to cause concerns and impact normal routines

Academic Institutions & Research Centers Segment to Account for Largest Revenue Share:

The academic institutions and research centers segment is expected to account for largest revenue share during the forecast period. Revenue growth can be attributed to factors such as high prevalence of genetic and rare diseases, rise in funds for genomic research, increasing healthcare spending, and growing demand for advanced therapeutics and personalized medicine.

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Personalized Medicine by Synthesis Segment Register Robust Revenue CAGR:

The personalized medicine segment is expected to register robust revenue CAGR between 2021 and 2028 owing to growing demand for customized therapeutic approaches, rising incidence of rare diseases and cancer, and increasing funds for developing innovative drugs.

North America To Lead In Terms of Revenue Share:

North America is expected to dominate other regional markets in terms of revenue share over the forecast period owing to high prevalence of genetic disorders, availability of funds by public and private sectors, and presence of leading market players. In addition, presence of well-developed research facilities, increasing investments for genomics and cancer-based research, and high usage of exome sequencing for diagnosis of rare diseases are expected to drive North America market growth during the forecast period.

Major Companies in the Market Include:

  • llumina, Inc.
  • Thermo Fisher Scientific, Inc.
  • Agilent Technologies
  • Hoffman-La Roche AG
  • Eurofins Genomics, Inc.
  • GENEWIZ, Inc.
  • Knome, Inc.
  • Macrogen, Inc.
  • Ambry Genetics
  • Beijing Genomics Institute

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For the purpose of this report, Emergen Research has segmented the global whole exome sequencing market is segmented into product, technology, application, end use, and region:

Product Outlook (Revenue, USD Billion; 2018–2028)

  • Systems
  • Kits
    • DNA Fragmentation End Repair, A-Tailing and Size Selection
    • Library Preparation Kits
    • Target Enrichment Kits
  • Services
    • Sequencing Services
    • Data Analysis Services

Technology Outlook (Revenue, USD Billion; 2018–2028)

  • Sequencing by Synthesis
  • Ion Semiconductor Sequencing
  • Others

Application Outlook (Revenue, USD Billion; 2018–2028)

  • Diagnostics
  • Cancer
  • Monogenic Disorders
  • Diabetes
  • Drug Discovery & Development
  • Personalized Medicine
  • Others

End Use Outlook (Revenue, USD Billion; 2018–2028)

  • Academic Institutions & Research Centers
  • Hospitals & Clinics
  • Pharmaceutical and Biotechnology Companies
  • Others

Regional Outlook (Revenue, USD Billion; 2018–2028)

  • North America
    • U.S.
    • Canada
    • Mexico
  • Europe
    • Germany
    • France
    • U.K.
    • BENELUX
    • Italy
    • Rest of Europe
  • Asia Pacific
    • China
    • India
    • Japan
    • South Korea
    • Rest of APAC
  • Latin America
    • Brazil
    • Rest of LATAM
  • Middle East & Africa
    • Saudi Arabia
    • U.A.E.
    • South Africa
    • Turkey
    • Rest of MEA

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