Increasing adoption of whole exome sequencing (WES) technology in the medical sector and rising number of strategic alliances between pharmaceutical companies and research institutes are some key factors supporting market revenue growth.
Increasing adoption of whole exome sequencing (WES) technology in the medical sector and rising number of strategic alliances between pharmaceutical companies and research institutes are some key factors supporting market revenue growth
Market Dynamics:
Key factors contributing to revenue growth of the global whole exome sequencing market are rapid incorporation of emerging technologies in the life sciences industry, increasing pharmaceutical and biotechnological research & development activities, rising awareness of the advantages of whole exome sequencing technology over whole genome sequencing, and latest advances in the field of genomic research.
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Whole exome sequencing, shortened to WES, is a next-generation sequencing (NGS) technique that involves sequencing of the protein-coding regions of the genome. The technique also involves screening and identification of mutations and variations in these regions. Whole exome sequencing technique finds applications in the diagnosis and treatment of chronic diseases such as diabetes, cancer, and coronary heart disease. Most diseases causing mutations occur in exons, which are the coding sections of a DNA or RNA transcript and make up around 1% of an individual’s whole genome. Whole exome sequencing technique is increasingly being used by researchers to study exome and genome sequences and identify and determine the genetic variations associated with various diseases. The technique is more cost-effective compared to the whole genome sequencing technique, and it accurately identifies the genetic variations that alter protein sequences.
Increasing government and private investments in R&D activities in the healthcare sector and growing need for advanced diagnostic tools are other key factors driving the global market revenue growth. However, market revenue growth can be hampered to some extent over the forecast period, owing to factors such as lack of skilled healthcare professionals and rising concerns and ethical issues associated with the whole exome sequencing technique.
COVID-19 Impact Analysis:
- Social distancing and restrictions severely disrupted businesses and operations
- Lockdowns caused disruptions in transportation and logistics
- Impacted manufacturing activities and mining operations globally
- Took a toll on economy of various countries
- Caused sudden and drastic downturn in economic activity
- Disrupted agriculture, fisheries, dairy, and other sectors
- Caused loss of employment and financial crisis
- Supply impacts were further compounded owing to reduced disposable income
- Emergence of variants continue to cause concerns and impact normal routines
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Services Segment Accounted for Largest Revenue Share in 2020:
The services segment – which is sub-segmented into sequencing and data analysis services – dominated other segments in terms of revenue share in the global market in 2020. Growing demand for high-throughput sequencing and data analysis services due to certain advantages such as low-cost sequencing and data management capabilities and advanced bioinformatics visualization is one of the major factors contributing to revenue growth of this segment.
Research Centers & Academic Institutions Segment to Account for Fastest Revenue CAGR:
The research centers & academic institutions segment is expected to register the fastest revenue growth rate in the global market over the forecast period. Rising demand for advanced therapeutics and personalized medicine, increasing government and private investments in research & development activities in the field of genomics, and increasing use of whole exome sequencing technique in in diagnosis and treatment of cancer and other chronic diseases are some of the major factors supporting this segment’s revenue growth.
North America Accounted for Largest Revenue Share in 2020:
Among regional markets, the North America whole exome sequencing market accounted for the largest revenue share in the global market in 2020. Major factors providing impetus to the North America market revenue growth are rising prevalence of chronic and genetic diseases, increasing demand for personalized medicine, increasing adoption of whole exome sequencing technology to develop advanced medical diagnostics, increasing R&D activities in the fields of genomics and proteomics, and presence of key market players in the region, such as Agilent Technologies, Illumina, Inc., Life Technologies, and Knome, Inc..
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Major Companies in the Global Whole Exome Sequencing Market Include:
- Illumina, Inc.
- Life Technologies
- Roche NimbleGen, Inc.
- Agilent Technologies
- BGI (Beijing Genomics Institute)
- Eurofins Genomics, Inc.
- Sengenics
- GENEWIZ, Inc.
- Knome, Inc.
- Macrogen, Inc.
- Ambry Genetics
For the purpose of this report, Emergen Research has segmented the global whole exome sequencing market based on product & service type, technology, application, end-use, and region:
Product & Service Type Outlook (Revenue, USD Billion; 2018-2028)
- Products
- Systems
- Kits
- DNA Fragmentation End Repair, A-Tailing and Size Selection
- Library Preparation Kits
- Target Enrichment Kits
- Services
- Sequencing Services
- Data Analysis Services
- Others
Technology Outlook (Revenue, USD Billion; 2018-2028)
- Sequencing by Synthesis
- Ion Semiconductor Sequencing
- Others
Application Outlook (Revenue, USD Billion; 2018-2028)
- Diagnostics
- Cancer
- Monogenic Disorders
- Diabetes
- Drug Discovery and Development
- Personalized Medicine
- Agriculture and Animal Research
- Others
End-use Outlook (Revenue, USD Billion; 2018-2028)
- Hospitals & Clinics
- Pharmaceutical and Biotechnology Companies
- Research Centers & Academic Institutes
- Others
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Region Outlook (Revenue, USD Billion; 2018-2028)
- North America
- U.S.
- Canada
- Mexico
- Europe
- Germany
- France
- U.K.
- Italy
- Spain
- BENELUX
- Rest of Europe
- Asia Pacific
- China
- India
- Japan
- South Korea
- Rest of Asia Pacific
- Latin America
- Brazil
- Rest of Latin America
- Middle East & Africa
- Saudi Arabia
- U.A.E.
- South Africa
- Turkey
- Rest of Middle East & Africa
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