NICE, France & WALTHAM, Mass.--(BUSINESS WIRE)--Avila Therapeutics™, Inc., a biotechnology company developing novel covalent drugs that treat diseases through protein silencing, presented results of preclinical studies on its highly selective, pan-genotype, small molecule Hepatitis C Virus (HCV) protease inhibitor, AVL-181. The data showed that AVL-181 bonds selectively, covalently and irreversibly to HCV protease (also known as “NS3/4A”), thus silencing a key protein necessary for successful viral replication resulting in a prolonged duration of action.