Fullerton, Calif. (January 9, 2007) – Beckman Coulter, Inc. introduces the IOTest® Anti-p75/AIRM1 (adhesion inhibitory receptor molecule 1)-PE conjugated antibody, featuring an exclusive clone, Z176. p75/AIRM1, whose ligand is not yet known, is an inhibitory molecule expressed by natural killer (NK) and myelomonocytic cells. Engagement of p75/AIRM1 with a purified monoclonal antibody has been shown in recent scientific papers to inhibit the proliferation of myeloid cells, and p75/AIRM1 may represent a useful marker for studying the normal myeloid differentiation process. The new reagent is the only commercially available antibody against the p75/AIRM1 molecule. It can be used with the multicolor NK cell gating reagent, CD3-FITC/CD56-PC5, and completes a line of PE-conjugated NK markers, available only from Beckman Coulter.
