Novo Grilled by Senate, PhRMA’s IRA Win and BMS’ KarXT Awaits Approval

New revelations from the showdown between Novo Nordisk’s CEO and Bernie Sanders’ Senate health committee Tuesday; PhRMA’s legal victory in IRA case; the federal interest rate cut and anticipated approval for schizophrenia.

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Novo Nordisk CEO Lars Fruergaard Jørgensen ⁠testified⁠ Tuesday in front of Sen. Bernie Sanders’ Senate health committee regarding the prices of Ozempic and Wegovy—with some interesting takeaways. Meanwhile, PhRMA scored a rare win as the Fifth Circuit Court of Appeals ⁠ruled⁠ in the trade group’s favor, sending its complaint against the Inflation Reduction Act (IRA) back to a lower Texas court. Looking ahead, 15 more drugs are expected to be negotiated under the IRA next year, including Novo’s Ozempic.

Last week, the Federal Reserve cut the ⁠federal interest rate⁠ by half a percentage point—a move that was expected and met with a collective shrug from the biotech market, with experts skeptical of its impact.

Elsewhere, the ⁠schizophrenia space⁠ is ⁠gearing up⁠ for an FDA decision on BMS’ KarXT. If approved, KarXT would be the first novel drug for the neuropsychiatric disease in decades. And on the obesity front, Novo’s ⁠oral cannabinoid receptor 1 drug⁠ elicited impressive weight loss in a Phase IIa trial, with some adverse events, and young startup Metsera ⁠touted⁠ robust Phase I data for its injectable GLP-1 candidate.

Heather McKenzie is senior editor at BioSpace. You can reach her at heather.mckenzie@biospace.com. Also follow her on LinkedIn.
Greg is a seasoned editor/writer who has covered the healthcare, life sciences and medical device industries for several tech trade publications. Follow him on LinkedIn.
Jef Akst is managing editor of BioSpace. You can reach her at jef.akst@biospace.com. Follow her on LinkedIn and Twitter @JefAkst.
Annalee Armstrong is senior editor at BioSpace. You can reach her at  annalee.armstrong@biospace.com. Follow her on LinkedIn.
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