This is the latest rundown of people coming and going from executive positions at biopharma companies that BioSpace covers. This regular column highlights the hired, fired, retired, promoted or resigning, as well as those personally named in lawsuits.
Pictured: A red illustration of a businessman walking through a door/iStock, lerbank
Welcome to the second in a regular series of rundowns of people coming and going from executive positions at biopharma companies that BioSpace covers. This column will highlight the hired, fired, retired, promoted or resigning, as well as those personally named in lawsuits.
While there were no blockbuster moves in the last two weeks on the scale of the Feb. 21 announcement that CEO Richard Gonzalez will soon retire from AbbVie, some less prominent biopharmas shook up their C-suites and others looked toward the next step of growth. Notably, Sumitomo named a new executive officer as part of a restructuring that will include the closure of its CNS sales department, and Kineta halted the enrollment of a clinical trial and cut most of its small staff as it ponders a sale or even liquidation. Meanwhile, IDRx, a member of BioSpace’s 2023 NexGen class, snapped up two execs from Theseus Pharmaceuticals.
Alcanza Clinical Research
Research facilities network Alcanza Clinical Research has named James Clark its first-ever chief medical officer. Clinical trials specialist Clark was owner and CEO of Charlottesville Medical Research, a Virginia facility that he sold to Alcanza in 2022.
Capsida Biotherapeutics
Capsida Biotherapeutics has promoted Rob Murphy to chief manufacturing and quality officer from vice president of technical operations. In this role, Murphy will oversee the gene therapy company’s cGMP manufacturing, process development and analytics as Capsida ramps up production of engineered adeno-associated virus–based treatments.
Cellipont Bioservices
CDMO Cellipont Bioservices has hired Edwin Beale as chief commercial officer. The firm opened a 76,000-square-foot cell therapy manufacturing plant in The Woodlands, Texas, last week. The facility will house a center of excellence in cryopreservation as part of a collaboration with Evia Bio.
IDRx
IDRx has hired two former Theseus Pharmaceuticals executives to lead the company. Tim Clackson takes over as CEO and Brad Dahms is the new CFO and chief business officer at the Plymouth, Mass.–based clinical-stage targeted cancer therapy startup, which placed 8th in BioSpace’s 2023 NexGen class. Cofounder Ben Auspitz, who relinquished the top role, has been named IDRx chairman.
Moligo Technologies
Moligo Technologies has named John Kuijpers chief business officer to lead commercialization of the firm’s long, single-stranded DNA for industrial use. The Swedish company has a collaboration with Nationwide Children’s Hospital in Columbus, Ohio, to support research into gene therapies for cystic fibrosis and related conditions.
NeoVac
NeoVac, a London-based developer of RNA-lipid nanoparticle vaccines and treatments, has hired Heinrich Haas as CTO. Haas previously was VP of RNA formulation and drug delivery at BioNTech.
Sumitomo Pharma
As part of a restructuring that will result in the loss of 400 jobs in North America and the dissolution of its CNS sales department, Sumitomo Pharma said that current Chief Strategy Officer Tsutomu Nakagawa has been promoted to president and CEO, effective April 1. At the same time, Yutaka Wakemi, current vice president in charge of global corporate strategy, will add executive officer to his title. Three executives, Takuya Taguchi, Myrtle Potter and Armin Szegedi, are scheduled to depart March 31. Sumitomo recently reported disappointing sales of three of its drugs.
Velsera
Velsera has brought in Jamie Littlejohns as CEO to succeed interim leader Hans Cobben, who has returned to his role as board chairman. Littlejohns joined the computational biology company from McKinsey, where he led the consulting firm’s European healthcare and life science private equity practice. He has served as an external adviser to Velsera since 2022, when the company was formed from the merger of Pierian Dx, Seven Bridges and UgenTec.
Anagenex
Anagenex, an artificial intelligence–driven data generation company supporting small molecule drug discovery, has named Adrian Schreyer chief technology officer. The firm has a nascent research collaboration with Nimbus Therapeutics. Schreyer is former CTO and a founding employee of Exscientia.
OncoNano Medicine
OncoNano Medicine has promoted Kartik Krishnan to CEO from president and head of R&D, succeeding Martin Driscoll. The Southlake, Texas–based immune-oncology company also promoted Melissa Paoloni to executive VP and chief operating officer. OncoNano has a Phase I trial underway of its ONM-501 dual-activating polyvalent STING agonist for patients with advanced solid tumors and lymphomas.
Fore Biotherapeutics
Fore Biotherapeutics has brought in William Hinshaw to serve as CEO and board director. Hinshaw, former president, CEO and board member of Axcella Therapeutics, previously headed the U.S. oncology business of Novartis. Fore’s pipeline includes lead asset plixorafenib, a small molecule selective inhibitor of mutated BRAF that is currently in a Phase I/IIa clinical trial in patients with solid tumors.
Ionis Pharmaceuticals
Ionis Pharmaceuticals has rehired Kyle Jenne to serve as executive VP and chief global strategy officer as the Carlsbad, Calif.–based company prepares to launch its first commercial products. Jenne is replacing Onaiza Cadoret-Manier as head of global project strategy; Cadoret-Manier will depart March 15 but serve as an advisor to Ionis for an unspecified time period. The firm in December received FDA approval for Wainua (eplontersen), a therapy it codeveloped with AstraZeneca for treatment of adult polyneuropathy of hereditary transthyretin-mediated amyloidosis.
Alvotech
Biosimilars developer Alvotech announced the departure of Chief Quality Officer Sandra Casaca. She has been replaced on an interim basis by Christina Siniscalchi, who recently held a similar title at Alvogen. Days earlier, Alvotech and partner Teva Pharmaceuticals received FDA approval for Simlandi (adalimumab-ryvk), a biosimilar of AbbVie’s Humira (adalimumab).
Kineta
Kineta announced that it would eliminate the positions of CEO Shawn Iadonato and General Counsel Pauline Kenny as part of a reduction of seven jobs, or 64% of the company’s workforce. Iadonato and Kenny will stay on through the end of the year as Kineta considers a sale, acquisition, liquidation or other alternative. The firm has also stopped enrolling patients in its VISTA-101 Phase I/II trial for its KVA12123 compound for advanced solid tumors.
Corbus Pharmaceuticals
Corbus Pharmaceuticals has named Dominic Smethurst CMO to lead clinical development of a portfolio of investigational cancer drugs, including CRB-701, a Nectin-4 antibody-drug conjugate. The firm recently closed a $94.5 million public stock offering.
Bexion Pharmaceuticals
Bexion Pharmaceuticals has appointed a new CMO, Tariq Arshad, an oncologist who previously led R&D at Qualigen Therapeutics. Bexion is developing biologics to treat solid tumors and chemotherapy-induced peripheral neuropathy.
Nicox
Nicox fired CEO Andreas Segerros and replaced him with Gavin Spencer on the same day that the French ophthalmology drug company announced a restructuring of its debt to extend its cash runway to November 2024. The firm is concentrating its efforts on landing new financing to complete a Phase III trial of its lead asset, an investigational glaucoma therapy called NCX 470, by generating enough data to file a New Drug Application with the FDA. Nicox recently inked a partnership with Kowa to develop and commercialize the drug in Japan.
Neil Versel is the business editor at BioSpace. You can reach him at neil.versel@biospace.com. Follow him on LinkedIn or X.
Correction (March 13): This story was updated to clarify executive changes at Sumitomo Pharma. BioSpace regrets the error.
