The global CAR T-cells therapy market size reached USD 1.29 Billion in 2021 and is expected to register a revenue CAGR of 24.9% during the forecast period, according to latest analysis by Emergen Research.
The global CAR T-cells therapy market size reached USD 1.29 Billion in 2021 and is expected to register a revenue CAGR of 24.9% during the forecast period, according to latest analysis by Emergen Research. The rising prevalence of blood cancer is one of the major market growth drivers.
According to the National Cancer Institute, the global incidence rate of leukemia was 22.3 per 100,000 individuals in 2018. The high cost of this therapy and stringent regulations are some of the key challenges faced by market players. However, technological advancements and government initiatives are expected to create new opportunities for market growth over the forecast period.
Rapidly expanding clinical trial activities and recent commercialization of CAR-T cell therapy is expected to fuel the market growth over the forecast period. Technological advancements in cell engineering and manufacturing processes have resulted in improved patient outcomes and increased survival rates. Moreover, industry players are focused on developing next generation CAR-T cells with enhanced efficacy and safety profiles.
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For instance, in May 2019, Bluebird Bio Inc. initiated phase 1/2 clinical trials of its next-generation CAR T cell therapy, bb2121 in patients with relapsed or refractory multiple myeloma who have received at least three prior lines of therapy, including a proteasome inhibitor and an immunomodulatory drug. Such development activities are expected to create a significant opportunity for the market to grow over the next eight years.
Chimeric antigen receptor cell therapy is a technique used to target and kill cancer cells using a patient’s own immune system. CAR-T therapy alters a person’s T cells, which are a type of white blood cell, to recognize and attack cancer cells. This treatment is personalize and can be used to treat certain types of leukemia and lymphoma that have not responded well to other treatments.
Some Key Highlights From the Report
- Some major companies in the global market report include Novartis AG, Pfizer Inc., CARsgen Therapeutics Co., Ltd, Daiichi Sankyo Company, Limited, Bristol-Myers Squibb Company, Astellas Pharma Inc., BioNTech SE, Biocad, F. Hoffmann-La Roche Ltd., and Eli Lilly and Company.
- The diffuse large B-cell lymphoma segment accounted for the largest share of the CAR-T cell therapy market in 2019.The high efficacy and availability of approved CAR-T cell therapies are the major factors driving the growth of this segment.
- Based on cell type, the autologous segment is estimated to dominate the global market in 2021. This segment is expected to grow at a revenue-based CAGR of 26.4% over the forecast period. The allogeneic segment is projected to be the fastest-growing segment during the forecast period, with a revenue-based CAGR of 26.9%.
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- The hospital segment is estimated to account for the largest share of the global market in 2021. This segment is expected to grow at a revenue-based CAGR of 25.2% over the forecast period. The ambulatory surgical center segment is projected to be the fastest-growing segment during the forecast period, with a revenue-based CAGR of 26.4%.
- North America is estimated to account for the largest share of the global market in 2021. This regional segment is expected to grow at a revenue-based CAGR of 26.1% over the forecast period. The Asia Pacific region is projected to be the fastest-growing region during the forecast period, with a revenue-based CAGR of 27.2%.
- The market in Europe and the Asia Pacific would grow at a faster rate over the forecast period. The growth in these regions is attributed to rise in government initiatives, increasing research and development activities, and growing demand for CAR-T cell therapies. Moreover, large patient population base would further drive market growth across developing countries of these regions. However, stringent regulations and high cost associated with the treatment would limit market growth to some extent.
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Emergen Research has segmented the global CAR-T cells therapy market on the basis of type, indication, end-use, and region:
- Type Outlook (Revenue, USD Billion; 2019-2030)
- Abecma
- Breyanzi
- Kymriah
- Yescarta
- Indication Outlook (Revenue, USD Billion; 2019-2030)
- Diffuse Large B-cell Lymphoma (DLBCL)
- Acute Lymphoblastic Leukemia (ALL)
- Chronic Lymphoblastic Leukemia (CLL)
- Multiple Myeloma (MM)
- Follicular Lymphoma (FL)
- Others
- End-Use Outlook (Revenue, USD Billion; 2019-2030)
- Hospitals
- Cancer Treatment Centers
- Regional Outlook (Revenue, USD Billion; 2019-2030)
- North America
- U.S.
- Canada
- Mexico
- Europe
- Germany
- France
- U.K.
- Italy
- Spain
- Benelux
- Rest of Europe
- Asia Pacific
- China
- India
- Japan
- South Korea
- Rest of APAC
- Latin America
- Brazil
- Rest of LATAM
- Middle East & Africa
- Saudi Arabia
- U.A.E.
- South Africa
- Turkey
- Rest of MEA
- North America
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