Cell Separation Market Size to Hit USD 30.8 Billion by 2030

According to Nova one advisor, the global Cell Separation market size is expected to hit around USD 30.8 billion by 2030 from valued at USD 7.6 billion in 2021 and growing at a CAGR of 19.8% from 2022 to 2030

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Key Takeaways:

• By product, the consumables segment dominated the market in 2020, owing to its repetitive use in research applications
• By application, the biomolecule isolation segment dominated the market in 2020, due to increasing R&D initiatives for the development of innovative biologics
• The research laboratories and institutes segment accounted for the largest revenue share in the end-use segment in 2020, owing to increasing R&D initiatives by them in the field of oncology and neuroscience
• The high cost of cell isolation products is the most critical restraining factor for the overall market growth
• North America dominated the market with the largest revenue share owing to the presence of numerous large biopharmaceutical and biotechnology companies in the region
• In Asia Pacific, the market is projected to witness the highest CAGR during the forecast period due to the expanding biotech and pharma sectors in emerging markets such as China and India

Growing focus on biomolecule and cancer research, and rising incidence of chronic and infectious diseases, including the outbreak of COVID-19, are major factors contributing towards the growth of the market.

Cell separation products are widely used by researchers and healthcare professionals for the development and production of novel therapies such as gene therapies and regenerative medicines. Continuous technological advancements and the introduction of more efficient products by key players have significantly supported the market growth. For instance, in October 2020, Thermo Fisher Scientific, a U.S.-based prominent player in the field, launched its new Gibco CTS Rotea Counterflow Centrifugation System. This new system gives processing versatility to help in a broad range of protocols for cell separation. Also, increasing public-private initiatives and investments to facilitate stem and gene therapy development in potential emerging countries is anticipated to create a lucrative environment for market growth. In February 2020, the Global Institute of Stem Cell Therapy and Research (GIOSTAR), a regenerative medicine provider, established a stem cell/cancer research center in India.

Furthermore, the high prevalence of chronic diseases, such as cancer, and extensive R&D activities by leading biotech and pharma players to develop novel biological therapies are expected to fuel market growth. As per the American Cancer Society’s estimates, in 2021, around 1.9 million new cases of cancer are estimated to be diagnosed in the U.S., which will lead to around 608,570 deaths. Moreover, following the outbreak of COVID‐19, several U.S.-based companies are involved in extensive research for the development of novel vaccines and therapeutics, thereby driving the market.

Report Scope of the Cell Separation Market

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Product Insights

In 2021, the consumables segment dominated the market for cell separation and accounted for the largest revenue share of 63.3%. This segment held the largest market share due to repeated purchases of consumables. In addition, rising investments in R&D by biotechnology and biopharmaceutical companies for the development of advanced biologics including monoclonal antibodies and vaccines are also driving the segment. Thus, the demand for consumables is also expected to remain high during the forecast period.

The instruments segment is estimated to exhibit a lucrative growth rate during the forecast period, due to product advancements. Technological advancement in instruments provides efficient cell separation in research, diagnostics, and therapeutics application. Thus, the industry for instruments is anticipated to witness significant growth during the forecast period. However, the high cost of instruments is expected to restrain the market growth.

Cell Type Insights

The human cell segment dominated the market for cell separation and held the largest revenue share of 45.8% in 2021. Rising focus on human and cancer research and varied applications of isolated human cells in biopharmaceuticals development, clinical trials, and research are among the major factors contributing to its largest share. Moreover, favorable reimbursement policies pertaining to personalized medicine in developed countries further boost the demand for human cell isolation.

The animal cells segment is anticipated to exhibit a lucrative growth rate during the forecast period. The growing focus of government, private, and healthcare companies on new drug discoveries and development is a key factor driving the segment growth. Drug discovery and development involve animal cells’ use to examine efficacy, the pharmacokinetics of new drug molecules, and preliminary toxicity.

Technique Insights

The centrifugation segment dominated the market for cell separation and held the largest revenue share of 43.7% in 2021. This is due to the extensive usage of this technique by academic institutes, research laboratories, and biotechnology and biopharmaceutical companies. Centrifugation is one of the most important steps in cell isolation. Density gradient centrifugation and differential centrifugation are most commonly used for cell isolation. Density gradient centrifugation makes use of molecular weights of the particles to be separated, whereas differential centrifugation makes use of a lysate to break cell membranes to separate them.

The surface marker and filtration segments are expected to witness significant growth in the near future. Rising investments in manufacturing infrastructure by companies and product advancements are prime factors supporting the growth of this segment. Manufacturers are engaged in the usage of advanced filtration system surface markers for production and research processes to ensure a better quality of the end product.

Application Insights

The biomolecule isolation segment dominated the market for cell separation and accounted for the highest revenue share of 31.8% in 2021. The growing focus on the production of biopharmaceuticals, including biosimilar, monoclonal antibodies, and recombinant proteins, is the most predominant factor contributing to its highest share. Also, increasing government funding for new drug development propels the market growth.

The cancer research and stem cell research segments are projected to exhibit lucrative growth over the study period. Rising investment in cell-based research by companies and research laboratories is a key factor that can be attributed to the segment growth. Several public-private organizations are investing heavily in cancer research owing to the increasing global incidence of cancer, thus, driving the demand for innovative separation solutions.

End-use Insights

The research laboratories and institutes segment accounted for the largest revenue share of 44.9% in 2021 and is expected to hold its position throughout the study period. This can be attributed to increasing R&D initiatives by research institutions to develop novel therapies in oncology and neuroscience. The growing number of research institutes and laboratories across the globe is also anticipated to be a major driver of the segment. For instance, in April 2017, the New York Stem Cell Foundation (NYSCF) opened a new Research Institute in Manhattan, which is focused on conducting the most advanced stem cell research.

The biotechnology and pharmaceutical companies segment exhibited significant growth over the forecast period due to increasing R&D investment by these companies for the development of new products. These companies are involved in extensive R&D activities for the development of new-generation therapeutics, which require cell separation techniques. Furthermore, increasing research activities by commercial organizations to develop efficient vaccine and therapeutics for COVID-19 are anticipated to create high demand for cell separation solutions, thereby supporting segment growth.

Regional Insights

North America dominated the cell separation market and held the largest revenue share of 39.7% in 2021. This can be attributed to well-established pharmaceutical and biotech industries, and the high adoption of technologically advanced solutions in the U.S. Furthermore, extensive research activities by research universities in the field of cell therapies have created a huge demand for cell separation solutions. In addition, the high prevalence of chronic and infectious diseases, including the outbreak of COVID-19, has led to an increase in the demand for cell separation solutions for research and clinical applications.

In Asia Pacific, the market for cell separation is projected to witness significant growth due to growing pharmaceutical and biotechnology industries in emerging economies such as China and India. In addition, growth in healthcare expenditure and increase in market penetration of major global players in key Asia Pacific countries are factors expected to drive the segment over the forecast period. Furthermore, continuous stem and gene therapy research initiatives in Japan, China, and South Korea have further boosted the demand for cell separation solutions in the region.

Some of the prominent players in the Cell Separation Market include:

• Thermo Fisher Scientific, Inc.
• Becton, Dickinson and Company
• Danaher
  • Beckman Coulter, Inc.
  • Cytiva
• Terumo Corporation
• STEMCELL Technologies Inc.
• Bio-Rad Laboratories, Inc.
• Merck KGaA

Segments Covered in the Report

This report forecasts revenue growth at global, regional, and country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2017 to 2030. For this study, Nova one advisor, Inc. has segmented the global Cell Separation market

• Product
  • Consumables
    • Reagents, Kits, Media, and Sera
    • Beads
    • Disposables
  • Instruments
    • Centrifuges
    • Flow Cytometers
    • Filtration Systems
    • Magnetic-activated Cell Separator Systems

• Cell Type
  • Human Cells
  • Animal Cells

• Technique
  • Centrifugation
  • Surface Marker
  • Filtration

• Application
  • Biomolecule Isolation
  • Cancer Research
  • Stem Cell Research
  • Tissue Regeneration
  • In Vitro Diagnostics
  • Therapeutics

• End-use
  • Research Laboratories and Institutes
  • Hospitals and Diagnostic Laboratories
  • Cell Banks
  • Biotechnology and Biopharmaceutical Companies

By Region

• North America
• Europe
• Asia Pacific
• Latin America
• Middle East & Africa

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