Cell Transfection Market Demand is Expanding at a Remarkable CAGR By 2032

The global cell transfection market is expected to expand at a remarkable CAGR during the forecast period from 2023 to 2032.

Transfection is a recombinant DNA technology method wherein foreign genomic material is deliberately introduced into a target organism. This synthetic method inserts naturally occurring chemical compounds such as deoxyribonucleic acid (DNA), ribonucleic acid (RNA), and oligonucleotides into a host cell nucleus, where it integrates into the host genome and causes intentional genetic alterations. The principle of transfection is the foundation of several genetic engineering and gene analysis technologies.

Transfection involves several chemical, physical, and biological procedures to facilitate the preparation and success of the actual process. Preparatory techniques such as magnet-assisted transfection and electroporation are used to enlarge the porousness of the host cell, allowing easy and unhindered entrance of the DNA. Co-transfection, cationic lipid transfection, electroporation, and in-vivo transfection are some of the approaches used for the actual introduction of foreign genetic material. Lentiviral transfection uses viral particles to transfect or transduce foreign material into the eukaryotic cells. Another method involves bacterial transformation via the horizontal transfer of foreign genetic material.

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Besides genetic engineering, the cell transfection market has applications in various fields, including therapeutics, diagnostics, and academic and industrial research. It is typically used in genomic studies during screening, RNA interference, gene expression, and in vivo research. These assays enable improved drug refinement in addition to promoting cellular research. Within the pharmaceutical industry, cell transfect has a vital role in the development and production of vaccines. Factors such as the growing prevalence of diseases, private and state initiatives, resource availability, partnerships and collaborations, and new treatment alternatives have been driving the cell transfection market in the past few decades. Similarly, technological innovations, discoveries, artificial intelligence (AI) and automation are expected to create new avenues to potentiate future growth.

Regional Stance:

Geographically speaking, North America had the biggest market share in terms of revenue in 2022. It is anticipated that the region will stay on this trajectory for the duration of the forecast period. This is because there are reliable manufacturers and substantial funding available to support research and development (R&D) on cancer medicines, precision medicine, and advanced cytological studies. The greater market potential in the region might increase the revenue of significant companies in the U.S. cell transfection industry.

An environment that is expected to be advantageous for established multinational manufacturers looking to expand their cell transfection business is expected to be provided by rising healthcare spending in Asia Pacific. Additionally, the patient pool in this area is growing, which presents unrealized market potential. This is complemented by aggressive government encouragement of the use of gene and cell therapy.

Growth Factors:

• India, China, and many other emerging economies provide an abundance of real estate as well as skilled labor. This makes these regions attractive assets for the establishment of dedicated manufacturing plants. Companies found it profitable to conduct non-central operations of the product life cycle in these areas. Public acknowledgement of various conditions affecting the overall well-being of the nation, followed by the subsequent development of healthcare infrastructure and increase in budget, have further potentiated the generation of necessary resources and workforce. These offshoring conventions have led to noteworthy prospects for businesses to enter the international market. Moreover, leniency in regulatory compliance and business and trade-promoting incentives aid these foreign ventures.
• Increasing awareness in terms of formerly overlooked conditions has appeared on the tracks of the global pandemic. The multitude of acknowledgements received for these hidden dangers generates lucrative possibilities for the growth of the healthcare industry, particularly the biotechnology sector. Some of these diseases utilize therapeutics based on genetic constituents. Cell transfection procedures guide the direction of the initial research conducted to understand the disease pathogenesis as well as to develop appropriate therapeutics. For instance, hereditary diseases depend on gene therapies to improve symptoms by targeting defective genes. Also, immunotherapies generally used in cancer and other chronic conditions depend on transfection products of the naturally occurring genes.

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Cell Transfection Market Scope

Market Potential:

Grants and other monetary investments provided by both private and state organizations offer minor investigators and small startups opportunities to conduct academic research on genetic studies without the pressure to produce a new drug. Numerous initiatives favor vaccine development, increasing prevalence and research on genetically inherited and chronic conditions, and immunomanipulative procedures actively promote cell transfection market growth. Pharmaceutical giants engage in strategic partnerships with each other or newer startups to develop products or technologies to match the changing trends in the healthcare sector. Partners share their proficiency and expertise to gain a foothold in the fiercely competitive industry.

Innovations in technology and cell and gene therapy options show substantial potential in the market. These options allow the market to develop in new directions, emerging as a game-changer, fulfilling the therapeutic needs associated with complex disorders. Pharmaceutical companies are slowly shifting their focus toward developing and commercializing these therapies.

Related Reports:

• Cell and Gene Supply Chain Services Market: The global cell and gene supply chain services market size reached USD 1.3 billion in 2022 and is expected to hit around USD 3.5 billion by 2032, poised to grow at a CAGR of 10.41% during the forecast period from 2023 to 2032.
  
• Cell Cryopreservation Market: The global cell cryopreservation market size is projected to hit around USD 60.89 billion by 2032 from USD 13.22 billion in 2023 and is growing at a CAGR of 18.50% during the forecast period from 2023 to 2032.
  
• Cell and Gene Therapy Clinical Trials Market: The global cell and gene therapy clinical trials market size is expected to hit around USD 40.98 billion by 2032 from USD 10.05 billion in 2022 and is poised to grow at a CAGR of 15.09% during the forecast period from 2023 to 2032.

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Industry Spotlight:

• In May 2022, AGC Biologics announced the expansion of its gene therapy manufacturing capacities and viral vector suspension technology at its commercial-grade Longmont site in Colorado. The advancement will enhance the firm’s viral vector and cell treatment services that have been commercially available since the third quarter of 2022.
• In February 2022, a provider of transfection reagents, Polypus, acquired a France-based DNA design and production services provider, e-Zyvec. The acquisition will aid the parent company in expanding its portfolio for custom-made DNA vectors and enhance its expertise in plasmid DNA vector engineering.
• In August 2023, SIV-infected rhesus macaques were treated with EBT-001 to target multiple regions of the virus genome to find a therapeutic intervention for HIV. CRISPR-Cas9 gene editing technology aided the study of proviral DNA as a potential tool for the treatment of HIV.

Market Key Players:

• Thermo Fisher Scientific, Inc.
• Promega Corporation
• Lonza
• QIAGEN
• F. Hoffmann-La Roche Ltd.
• Bio-Rad Laboratories Inc.
• Merck KGaA
• OriGene Technologies Inc.
• MaxCyte, Inc.
• POLYPLUS TRANSFECTION

Company Synopsis:

Bio-rad Laboratories Inc.

Bio-Rad is ranked in the world’s top five life science companies. It offers software, instruments, edibles, reagents, and other products and services catering to the necessities of various sectors such as cell biology, protein purification and quantitation, gene expression, drug discovery and manufacture, food safety, and others. In August 2022, Curiosity Diagnostics, a developer of cutting-edge technology solutions for the medical diagnostic and healthcare markets, was acquired by Bio-Rad Laboratories, Inc. The company, headquartered in Poland, was registered for a capital of $170 million. It consists of roughly $100 million in cash and up to $70 million in potential future milestone payments.

Lonza

Lonza is a Swiss Alps-based company founded in 1897. It is a globally favoured service provider for biotech, pharmaceutical, and nutrition companies. Lonza optimizes its innovative manufacturing technologies to deliver to its client’s tools to serve their patients and consumers. Boasting a workforce of more than 17,500 full-time individuals, the group caters to a wide range of services and products for their clients, from development to custom products to manufacturing active creations. In 2022, Lonza had 6.2 billion Swiss Franc revenue in sales with a CORE EBITDA of 2 billion. The company maintains a secondary listing on the SGX Singapore Exchange and shares on the SIX Swiss Exchange and Swiss Market Index.

Merck Group

The Merck Group is a German multinational company that possesses a intricate network of around 250 facilities. Headquartered in Darmstadt, Germany, the company deals mainly in science and technology. Merck’s operations are spread across 66 nations, boasting a workforce of about 60,000 hardworking and talented workers. The group primarily operates in Asia, Oceania, Europe, Africa, and the US, with research and development centers in Darmstadt, Boston, Tokyo, and Beijing and other smaller facilities in Israel, Taiwan, France, India, South Korea, and the UK. Merck’s 2022 financial report showed the net sales revenue to be 22,232 million euros.

Market Segmentation

By Method

• Electroporation
• Lipofection
• Calcium Phosphate
• Viral Transfection
• Others

By End User

• Academic and Research Institutes
• Pharmaceutical and Biotechnology Companies
• Contract Research Organizations
• Others

By Geography

• North America
• Europe
• Asia-Pacific
• Latin America
• Middle East and Africa

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