CNS Pharmaceuticals, Inc. (NASDAQ: CNSP) (“CNS” or the “Company”), a biopharmaceutical company specializing in the development of novel treatments for primary and metastatic cancers of the brain and central nervous system, today recognizes Glioblastoma (GBM) Awareness Day.
HOUSTON, July 22, 2020 /PRNewswire/ -- CNS PHARMACEUTICALS AG Inc. (NASDAQ: CNSP) (“CNS” or the “Company”), a biopharmaceutical company specializing in the development of novel treatments for primary and metastatic cancers of the brain and central nervous system, today recognizes Glioblastoma (GBM) Awareness Day. GBM is a highly aggressive and virtually incurable form of brain cancer. Every year, roughly 10,000 individuals in the United States are expected to succumb to glioblastoma. Accounting for more than 60% of all brain tumors in adults, it is estimated that more than 13,000 Americans will be diagnosed with GBM in 2020. For the past several decades, the survival outcomes and mortality rates for patients with GBM have improved only slightly. Patients diagnosed with GBM currently have a median survival time of 14-16 months, and a five-year survival rate of just 6.8%. CNS Pharmaceuticals is continuing to drive the development of Berubicin, a novel therapy for the treatment of glioblastoma. Berubicin is an anthracycline, a class of anticancer agents among the most powerful chemotherapy drugs and effective against more types of cancer than any other class of chemotherapeutic agents. Berubicin has demonstrated the potential to be one of the first anthracyclines to cross over the blood brain barrier and kill tumor cells in humans. In a Phase 1 human clinical trial under a prior developer, 44% of patients treated with Berubicin experienced a statistically significant improvement in progression-free survival and one patient experienced a durable complete response. As part of the Company’s efforts to initiate a Phase II trial in GBM by the end of the year, CNS Pharmaceuticals successfully engaged USA-based Pharmaceutics International, Inc., (Pii) and Italian BSP Pharmaceuticals S.p.A., (BSP) to produce Berubicin drug product. The Company decided to implement a dual-track drug product manufacturing strategy to mitigate COVID-19 related risks, diversify its supply chain, and reduce the risk that inefficiencies could impact the Company’s clinical timeline. Through contracting both a European and United States manufacturer, the Company also provided for localized availability of Berubicin for the upcoming Phase I Pediatric and Phase II adult studies in Poland, and the U.S. Phase II trial. CNS has completed synthesis of Berubicin Active Pharmaceutical Ingredient (API) and has shipped API to both Pii and BSP to prepare an injectable form of Berubicin ready for clinical use. CNS believes these are pivotal steps in allowing the Company to initiate clinical studies in GBM patients. “Among brain tumors, GBM remains an unmet need for patients, with bleak survival outcomes and mortality rates,” commented John Climaco, CEO of CNS Pharmaceuticals. “We would like to take the time today to recognize GBM Awareness Day, and draw attention to providing solutions to this very aggressive form of brain tumor which claims numerous lives every single year. Treating GBM and driving the clinical development of Berubicin remains a key priority for CNS Pharmaceuticals and we are extremely pleased to be making tremendous progress towards our upcoming trials to help these patients. We look forward to further investigating Berubicin’s potential to treat this deadly cancer in our upcoming Phase I Pediatric and Phase II adult studies in Poland and initiating our U.S. Phase II trial.” About Berubicin About CNS Pharmaceuticals, Inc. Forward-Looking Statements View original content to download multimedia:http://www.prnewswire.com/news-releases/cns-pharmaceuticals-recognizes-glioblastoma-awareness-day-301097747.html SOURCE CNS Pharmaceuticals, Inc. | ||
Company Codes: NASDAQ-NMS:CNSP |