IRVINE, Calif.--(BUSINESS WIRE)--CoreValve (www.corevalve.com) announced today that its patented ReValving System, consisting of a breakthrough 18-French-sized delivery catheter, was used to percutaneously implant its proprietary porcine pericardial tissue bioprostheses over the severely diseased aortic heart valves of four consecutive high-risk patients: two at the HELIOS Heart Center (HHC), Siegburg, Germany, by Prof. Eberhard Grube, and two at the University of Leipzig (Germany) Heart Center, by Prof. Gerhard Schuler.