In Vitro Fertilization Market Experiencing Rapid Expansion

According to Vision Research Reports, the global in vitro fertilization market size was estimated at USD 25.34 billion in 2023 and it is projected to hit around USD 43.57 billion by 2033 with a CAGR of 5.57% from 2024 to 2033. The IVF market growth is driven by an increasing infertility rates, advancements in IVF techniques, continuous improvements in IVF success rates, and increasing demand for preimplantation genetic testing.

In Vitro Fertilization Market Overview

In the reproductive medicine, in vitro fertilization (IVF) represents a revolutionary method, providing optimism for couples confronting infertility challenges. The IVF industry comprises various technologies, procedures, and services tailored to aiding individuals and couples in realizing successful pregnancies. With ongoing advancements in medical science, the IVF sector has experienced notable expansion, fueled by factors like rising infertility rates, advancements in assisted reproductive technologies (ART), and heightened awareness and acceptance of IVF procedures.

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Key Pointers

• Europe region led the market with the largest market share of 37% in 2023.
• By Instrument, the culture media segment held the largest revenue share of 41% in 2023.
• By Instrument, the disposable devices segment is projected to exhibit the fastest growth rate from 2024 to 2033.
• By Procedure Type, the frozen non-donor segment registered the maximum market share in 2023.
• By Providers, the fertility clinics segment had the largest market share in 2023.

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In Vitro Fertilization Market Trends:

• Rising Demand for Genetic Testing: Increased awareness and acceptance of genetic testing techniques, such as comprehensive chromosomal screening (CCS) and preimplantation genetic diagnosis (PGD), are driving demand for IVF procedures with a focus on selecting genetically healthy embryos.
• Expansion of LGBTQ+ Family Building: The LGBTQ+ community’s growing interest in family building through assisted reproductive technologies, including IVF and surrogacy, is fueling market growth and prompting clinics to offer inclusive services tailored to diverse family structures.
• Emergence of Low-Cost IVF Clinics: The proliferation of low-cost IVF clinics and alternative pricing models is making IVF more accessible to a broader segment of the population, driving competition and potentially reducing treatment costs.
• Telemedicine and Remote Monitoring: The integration of telemedicine platforms and remote monitoring technologies into IVF services allows for greater convenience, flexibility, and patient engagement throughout the treatment process, particularly in light of the COVID-19 pandemic.
• Focus on Patient-Centric Care: IVF clinics are increasingly prioritizing patient experience and satisfaction by offering personalized treatment plans, comprehensive support services, and transparent communication to ensure a positive journey through fertility treatment

In Vitro Fertilization Market Drivers:

• Increasing Prevalence of Infertility: The rising prevalence of infertility due to factors such as advanced maternal age, lifestyle changes, and medical conditions contributes to the growing demand for IVF services. As more couples experience difficulties conceiving naturally, they turn to assisted reproductive technologies like IVF as a solution.
• Advancements in Technology: Ongoing advancements in IVF technology, including improvements in embryo culture techniques, cryopreservation methods, and genetic screening technologies, enhance the success rates and safety of IVF procedures. These technological innovations attract patients seeking more effective and personalized fertility treatments.
• Growing Awareness and Acceptance: Increased awareness and acceptance of IVF as a viable option for achieving pregnancy contribute to market expansion. Education initiatives, media coverage, and celebrity endorsements have helped destigmatize infertility and promote IVF as a mainstream reproductive option.
• Expanding Demographic Trends: Changing demographic trends, such as delayed childbearing and increasing rates of same-sex couples and single individuals seeking parenthood, drive demand for IVF services. As individuals and couples postpone childbearing for various reasons, they rely on IVF to overcome age-related fertility challenges.
• Rising Healthcare Expenditure: Increasing healthcare expenditure and rising disposable incomes enable more individuals and couples to afford IVF treatments. Despite the high costs associated with IVF, patients are willing to invest in fertility services to fulfill their desire for parenthood, driving market expansion.

In Vitro Fertilization Market Challenges:

• Cost: IVF treatment can be prohibitively expensive for many couples. The high cost of procedures, medications, and associated services often leads to financial strain and may limit access to treatment.
• Ethical and Legal Concerns: IVF raises complex ethical and legal issues, such as the disposition of unused embryos, the potential for multiple pregnancies, and the use of preimplantation genetic testing. These concerns can vary widely across different jurisdictions and may impact the availability and regulation of IVF services.
• Success Rates: Despite advances in technology, IVF success rates remain variable, with factors such as age, underlying fertility issues, and treatment protocols influencing outcomes. Low success rates can lead to emotional distress for patients and may necessitate multiple treatment cycles, further increasing costs and stress.
• Emotional and Psychological Impact: The IVF process can be emotionally and psychologically challenging for patients, involving stress, anxiety, and feelings of uncertainty. The emotional toll of infertility and the rollercoaster of IVF treatment can strain relationships and impact overall well-being.
• Access and Equity: Access to IVF treatment may be limited by factors such as geographic location, socioeconomic status, and insurance coverage. Disparities in access can exacerbate existing inequalities in healthcare and reproductive services, leaving some individuals and couples unable to pursue treatment.

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Instrument Insights

The culture media segment held the highest market share, accounting for 41% of total revenue in 2023. This dominance is attributed to factors such as increased research efforts and the availability of funding aimed at enhancing culture media quality. In July 2022, FUJIFILM Irvine Scientific introduced Heavy Oil for Embryo Culture, a sterile mineral oil designed specifically for IVF procedures. This product addresses key concerns including pH balance, osmolality changes, and media preservation, thanks to its optimal viscosity.

The disposable devices segment is projected to exhibit the fastest growth rate during the forecast period. This growth is driven by industry players introducing disposable devices such as slides, needles, and chambers to ensure compliance with sterility and regulatory standards. These advancements are anticipated to boost the adoption of disposable IVF devices. Recent market innovations include disposable slides for sperm counting, imaging-based systems for isolating the best motile sperm, and the utilization of disposable microchips.

Procedure Type Insights

The frozen non-donor segment emerged as the dominant force in the market, capturing the largest revenue share in 2023, and is projected to experience the swiftest growth throughout the forecast period. This dominance can be attributed to factors such as its cost-effectiveness compared to fresh non-donor cycles and the less invasive nature of the procedure. Conversely, the fresh donor segment is expected to witness significant growth in the coming years. According to the 2020 National ART Summary report, approximately 1,477 ART cycles utilized fresh donors, with approximately 53.9% of transfers resulting in live-birth deliveries in the U.S.

While some centers offer risk-sharing plans and refunds for a limited number of cycles, the Advanced Fertility Center of Chicago stands out with its IVF reimbursement plan, providing a 100% refund for up to four cycles involving fresh embryos. There is a growing concern regarding sperm donation due to the lack of screening before donation, particularly as the Human Fertilization and Embryology Act 1990 does not cover fresh sperm donation. Consequently, there has been a revision of guidelines by HEFA, mandating a 180-day quarantine period for fresh sperm to undergo HIV screening. Additionally, NHS funding for fertility treatment using donated gametes is limited for homosexuals and single parents.

Providers Insights

The fertility clinics segment emerged as the market leader, capturing the largest revenue share in 2023, and is projected to experience the fastest growth over the forecast period. This dominance is attributed to the increasing demand for assisted reproductive technology (ART) treatments, resulting in a notable rise in the number of fertility clinics and ART centers. Factors such as cost-effectiveness, the availability of specialist expertise, and the minimal risk of Hospital-Acquired Infections (HAIs) are expected to propel the growth of the fertility clinics segment. It’s worth noting that IVF treatments are also conducted within hospital settings.

The hospitals and other settings segment are anticipated to witness significant growth at a considerable compound annual growth rate (CAGR) throughout the forecast period. Many multispecialty hospitals offer infertility treatments, including In-vitro Fertilization (IVF). The increased accessibility and availability of these treatments have led to a growing preference for hospitals for infertility care. However, it’s important to acknowledge that IVF treatments in hospitals typically incur higher costs compared to those in fertility clinics. This is primarily due to the necessity for highly skilled physicians and staff to perform these complex procedures. Consequently, the employment, remuneration, and training costs associated with maintaining a dedicated IVF staff in hospitals are considered less favorable. These costs are particularly pronounced in developed countries such as the U.S. and UK.

Regional Insights

Europe emerged as the dominant force in the market, capturing the largest revenue share of 37% in 2023. This can be attributed to several factors, including a significant rise in medical tourism, particularly with an increasing number of Americans opting to travel to the Czech Republic for more cost-effective IVF treatments. Additionally, individuals unable to afford overseas travel are now seeking IVF treatments within the United States at approximately one-third of the cost charged by domestic clinics. In July 2022, Fairtility received approval from the European Union to utilize artificial intelligence (AI) for embryo assessment. The EU’s new medical device regulation standards have facilitated the development of a commercially available AI tool, which holds the potential to enhance the success rate of IVF procedures.

North America is also poised to experience a surge in demand for fertility treatment in the coming years. Lifestyle changes, including inadequate nutrition, heightened stress levels, increased obesity rates, unhealthy dietary habits, escalating pollution levels, lack of physical activity, and the prevalence of medical conditions such as diabetes, have contributed to a higher incidence of infertility in the region. The growth in North America’s fertility market can be attributed to various factors, including the standardization of procedures through regulatory reforms, increased automation, government funding for egg and sperm storage, and the introduction of additional IVF treatments by industry players.

Key Market Developments

• In January 2021, Merck KGaA and Royal Philips forged a partnership to develop a digital solution aimed at delivering personalized fertility treatment.
• In January 2020, Merck KGaA obtained market authorization from the European Commission for its GONAL-f pen.
• In 2020, Fujifilm Irvine Scientific introduced a vitrification media solution named Vit Kit-NX.
• Also in 2020, Genea Ltd. and Hamilton Throne Ltd. joined forces to commercialize Genea Ltd.'s fertility products in North America.

In Vitro Fertilization Market Key Companies

• AmbroiseParé Group
• Amedes MVZ Cologne GmbH
• AMP Center St Roch
• AVA Clinic Scanfert
• Bangkok IVF center
• Betamedics
• Biofertility Center
• Bloom Fertility and Healthcare
• Bloom Fertility Center
• Bourn Hall Fertility Center

In Vitro Fertilization Market Segmentations:

By Instrument

• Disposable Devices
• Culture Media
  • Cryopreservation Media
  • Embryo Culture Media
  • Ovum Processing Media
  • Sperm Processing Media
• Equipment
  • Sperm Analyzer Systems
  • Imaging Systems
  • Ovum Aspiration Pumps
  • Micromanipulator Systems
  • Incubators
  • Gas Analyzers
  • Laser Systems
  • Cryosystems
  • Sperm Separation Devices
  • IVF Cabinets
  • Anti-vibration Tables
  • Witness Systems
  • Other

By Procedure Type

• Fresh Donor
• Frozen Donor
• Fresh Non-donor
• Frozen Non-donor

By Providers

• Fertility Clinics
• Hospitals & Others Setting

By Region

• North America
• Europe
• Asia Pacific
• Latin America
• Middle East & Africa (MEA)

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