KAHR Medical to Present at Oppenheimer’s Private Life Sciences Company Call Series

KAHR Medical today announced the company’s participation in Oppenheimer’s Private Life Sciences Company Call Series taking place virtually August 17-19, 2020.

JERUSALEM, Aug. 13, 2020 /PRNewswire/ -- KAHR Medical today announced the company’s participation in Oppenheimer’s Private Life Sciences Company Call Series taking place virtually August 17-19, 2020.

Yaron Pereg, Ph.D., Chief Executive Officer of KAHR Medical, has been invited to present an overview of the Company’s Fusion Protein Technology and its lead, clinical stage, anti-CD47 candidate developed for the treatment of solid tumors.

Details regarding the Company’s presentation are as follows:

Event: Oppenheimer’s Private Life Sciences Company Call Series
Date: Monday, August 17, 2020
Time: 12:15 PM ET12:50 PM ET

About DSP107

DSP107 targets CD47-overexpressing tumors, simultaneously blocking macrophage inhibitory signals and delivering an immune costimulatory signal to tumor antigen-specific, activated T-cells. CD47 is overexpressed on many cancer cells and binds SIRPα on immune phagocytic cells to produce a “don’t eat me” signal. DSP107 binds CD47 on cancer cells, blocking interaction with SIRPα and thus, blocking the “don’t eat me signal”. Simultaneously, DSP107 binds 41BB on T-cells, stimulating their activation. These activities lead to targeted immune activation through both macrophage and T-cell mediated tumor destruction. Recently, the U.S. Food and Drug Administration has cleared an investigational new drug (IND) application for DSP107. Under this IND, the Company intends to initiate a Phase I/II clinical trial to evaluate the safety, pharmacokinetics (PK) and pharmacodynamics (PD) of DSP107 as a monotherapy and in combination with Roche’s PD-L1-blocking checkpoint inhibitor (CPI) atezolizumab (Tecentriq®) in patients with advanced solid tumors. The study will be conducted at multiple centers in the United States and site activation activities are currently underway. The study will be conducted under a clinical collaboration with Roche.

About KAHR Medical

KAHR Medical develops the next generation of immuno-oncology drug candidates for the treatment of multiple types of cancer. Its proprietary technology enables the construction of targeted biological drugs generated by fusion of the active extracellular domains of a TNF-SF ligand and a type-I membrane protein. These Dual Signaling Proteins (DSPs) have two functional ends, which can simultaneously block and/or activate multiple reinforcing biological signals resulting in a synergistic outcome. The unique DSP composition ensures target activation and increased potency by assembling a high multimer protein structure which is essential for activation of the TNF receptor family. Investors in the Company include Flerie Invest AB, Oriella Limited a Consensus Business Group Limited subsidiary, HBL, Pavilion Capital, Mirae Asset, Korean Investment Partners and DSC Investments. For more information, please visit https://kahr-medical.com/.

Company contact:
Tsipi Haitovsky
Global Media Liaison
KAHR Medical
+972-52-5989-892
Tsipihai5@gmail.com

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SOURCE KAHR Medical

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