Krystle Vermes

UCLA Jonsson Comprehensive Cancer Center researchers and their colleagues announced on May 1 that they have discovered a drug that may help improve the overall survival rate in glioblastoma patients.
Notable will offer a grant to support the MDS Foundation’s education and advocacy efforts, and both companies will work closely to engage physicians, biopharmaceutical companies, health authorities and clinical trial organizations to collaborate on clinical trial designs.
These “backpacks” keep key immune cells in a tumor-killing state for up to five days after they approach a tumor.
Together, the companies will focus on the generation of novel small molecule inhibitors against specified deubiquitinase (DUB) targets, specifically for the treatment of neurodegenerative and other diseases.
FDA
Neurocrine Biosciences announced on Monday that it has received approval from the U.S. Food and Drug Administration for its once-daily oral drug, Ongentys, as an add-on treatment to levodopa/carbidopa for the treatment of Parkinson’s disease.
“Our goal is to successfully treat patients with severe inflammatory conditions and this is now possible through our alliance with Takeda,” said Denice Spero, president and chief business officer of ProThera.
“Our goal is to get information out to the community and to share data as soon as is humanly possible, so that we can help accelerate ongoing efforts in the scientific and medical communities,” said Alex K. Shalek, the Pfizer-Laubach Career Development Associate Professor of Chemistry.
The goal is to support the discovery and development of next-generation drug and engineered cell therapies, specifically with a focus on natural killer (NK) cells.
According to the research, published in Nature Cell Biology, targeted doses of doxorubicin could potentially inhibit the interaction between two molecular pathways that work together to encourage tumor growth.
“The excellent results seen in this Phase III study of 3-month duration suggest that daridorexant can fulfill this significant need for patients with insomnia,” said Dr. Thomas Roth, PhD, Director of the Sleep Disorder and Research Center at Henry Ford Hospital.