Mayo Clinic Researchers Discover Immune System Blocker At Work In Kidney Cancer

Mayo Clinic researchers have discovered a new and deadly player in the most common form of kidney cancer. They’ve shown that the molecule B7-H4 helps renal cell carcinoma (RCC) grow and spread by blocking the immune system. The Mayo researchers found that when B7-H4 is active, RCC patients are three times as likely to die from their cancer as RCC patients whose tumors don’t express B7-H4.

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