Membrane Oxygenators Market Size to Record US$ 241.5 Mn By 2030

According to a Vision Research Reports, the global Membrane Oxygenators market size is expected to be worth around US$ 241.5 Mn by 2030.

The global Membrane Oxygenators market size was valued at US$ 218.8 Mn in 2020 and is anticipated to grow at a CAGR of 3.5% during forecast period 2021 to 2030.

Report Highlights

• The hollow fiber membrane oxygenators segment dominated the market and accounted for the largest revenue share of 63.45% in 2020.
• The adult segment dominated the market and accounted for the largest revenue share of 56.3% in 2020.
• The neonate segment is anticipated to exhibit considerable CAGR over the forecast period.
• The respiratory segment dominated the membrane oxygenator market and accounted for the largest revenue share of 51.87% in 2020.
• The ECPR segment is likely to expand at a lucrative CAGR of 1.95% from 2021 to 2030.
• North America dominated the market and accounted for the largest revenue share of 40.4% in 2020.
• In Asia Pacific, the market is projected to exhibit the fastest CAGR of 2.2% over the forecast period.

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Growth Factors

 The increasing prevalence of respiratory and cardiovascular diseases, growing number of extracorporeal membrane oxygenator centers, rising adoption of membrane oxygenators as a bridge to lung transplantation are some of the major factors augmenting the market growth. In addition, training and conferences programs to increase awareness, technological advancements are anticipated to foster market growth. Membrane oxygenators were actively used in severe COVID-19 cases in the first two waves of the pandemic. The applications of membrane oxygenators are expanding rapidly. 

Leading market participants operating in this industry are focusing on developing technologically advanced membrane oxygenators. For instance, in January 2019, Terumo Medical Corporation launched the smallest, lowest prime volume, full-size adult oxygenator-Capiox NX19-with Ultraprime technology. Significant features of this device are it minimizes inflammatory response and provides higher efficiency microemboli removal. Portable adaptors and compact membrane oxygenators in ECMO circuits have also been developed, which help in the transportation of critically ill patients. The recent developments in medical devices are estimated to drive market growth.

Type Insights

The hollow fiber membrane oxygenators segment dominated the market and accounted for the largest revenue share of 63.45% in 2020. Hollow-fiber membrane oxygenators consist of a high number of fibers, with semi-porous walls and central lumen with holes large enough to move water through. These fibers are small enough so that proteins, mainly plasma proteins, can cover these holes, creating a semipermeable membrane or thin film through which gas exchange can occur. Hollow-fiber membrane oxygenators have holes that allow the emission of gas, quickly de-airing the fibers. Hence, these types of oxygenators have been integrated into few ECLS circuits for support after cardiac shock or arrest as a fast response system, driving the segment growth.

The flat sheet membrane oxygenators segment is the second largest segment with promising growth opportunities. These membrane oxygenators do not have holes in the membrane wall and depend on the permeability of plastic material, which allows gas transfer through the membranes. Flat sheet membrane oxygenators need flushing of the air outside the membrane with a soluble gas, including carbon dioxide, to avoid air trapping in a section with blood. In addition, flat sheet membrane oxygenators have a longer life span, with approval for use up to 14 days when compared to hollow-fiber oxygenators that need replacement within 6 to 12 hours, in most cases. This is expected to increase their adoption over the forecast period.

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Age Group Insights

The adult segment dominated the market and accounted for the largest revenue share of 56.3% in 2020. In the case of adult cardiac failure, the main indication that specifies the need for membrane oxygenation is cardiogenic shock. Advancement in membrane oxygenator technology has increased its application in the treatment of adults. Technological advancements include advanced designs, pump-less veno-arterial extracorporeal gas support devices, double-lumen cannula, and respiratory dialysis, which further drive segment growth. There are various factors to be considered before including ECMO in the adult treatment plan, such as the degree of organ failure, weight, comorbid conditions, and age, increasing its preference among patients.

The neonate segment is anticipated to exhibit considerable CAGR over the forecast period. A membrane oxygenator is commonly used to manage neonates with respiratory and cardiac failure. According to the Extracorporeal Life Support Organization (ELSO) registry report 2017, ECMO patients include 44.8% of neonates, with around 40,000 neonates treated with ECMO globally. Hence, the increasing number of neonates is expected to augment the demand for membrane oxygenators. However, the total number of neonates treated with membrane oxygenators is dropping significantly over time in large measure due to the recent development of minimally invasive modes of therapy for neonatal respiratory failure, limiting segment growth.

Application Insights

The respiratory segment dominated the membrane oxygenator market and accounted for the largest revenue share of 51.87% in 2020. Membrane oxygenators are commonly used to treat patients suffering from severe respiratory diseases, such as respiratory failure. They are used in pulmonary hypertension, respiratory distress syndrome, meconium aspiration syndrome, respiratory failure, and severe pneumonia, which indicates high applicability. In the case of respiratory illnesses, membrane oxygenators serve as artificial lungs, thus playing a critical role in supporting pulmonary function. Respiratory illnesses, including asthma, are increasing globally, which is expected to create demand for membrane oxygenators over the forecast period. According to the CDC, around 19.2 million adults of age 18 and above are suffering from asthma across the U.S. However, the possibility of complications such as infection, bleeding, and blood clot formation may adversely impact market growth.

The ECPR segment is likely to expand at a lucrative CAGR of 1.95% from 2021 to 2030. Centrifugal pumps integrated with hollow fiber oxygenators are used in ECPR. Various risks of this type of application are intracranial hemorrhage, which may prove to be fatal; reperfusion injury that may lead to sepsis; multiple organ failure; and/or neurological injury. The other risks include vascular injury, which may cause bleeding complications and functional cannula failures, impeding segment growth. In addition, failure in maintaining constant blood flow may lead to suboptimal support or death. Around 350,000 people suffer cardiac arrest annually in the U.S., and out of them, almost 1% to 2% of pediatric admissions require cardiopulmonary resuscitation (CPR). Hence, increasing cases of cardiac arrest are anticipated to foster segment growth.

Regional Insights

North America dominated the market and accounted for the largest revenue share of 40.4% in 2020. The market is expected to continue its dominance over the forecast period. Regionally, the market is segmented into North America, Latin America, Europe, Asia Pacific, and Middle East and Africa. The availability of well-developed primary, secondary, and tertiary care hospitals is supporting market growth in the region. Moreover, the presence of a well-developed reimbursement network, favorable government funding, and increasing awareness regarding membrane oxygenator machines are boosting its adoption in hospitals. Furthermore, technological advancements in membrane oxygenators are supporting market growth.

In Asia Pacific, the market is projected to exhibit the fastest CAGR of 2.2% over the forecast period. The growing prevalence of chronic diseases such as cardiopulmonary diseases due to unhealthy eating habits, excess tobacco consumption, and rising awareness about membrane oxygenators have led to a rise in its adoption rate in hospitals. Moreover, various government initiatives being undertaken and the success rate of ECMO systems during cardiothoracic surgeries are expected to boost the market growth. A large population with low per capita income in the Asia Pacific led to high demand for affordable treatment options. Multinational companies are planning to invest in developing countries such as China. This is further expected to boost the market over the forecast period.

Key Players

• Medtronic
• Fresenius SE & Co KGaA
• Getinge AB
• Terumo Medical Corporation
• MicroPort Scientific Corporation
• Nipro Medical Corporation

Market Segmentation

• Type Outlook 
  • Hollow Fiber Membrane Oxygenators
  • Flat Sheet Membrane Oxygenators
• Application Outlook
  • Respiratory
    • Respiratory failure
    • Pulmonary embolism
    • Acute respiratory distress syndrome
    • Pneumonia
    • COVID-19
  • Cardiac
    • Acute myocardial infarction
    • Myocarditis
    • Post-transplant complications
    • Decompensated cardiomyopathy
    • Cardiogenic shock
  • ECPR
• Age group Outlook 
  • Neonates
  • Pediatrics
  • Adults
• Regional Outlook
  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • Middle East & Africa

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