Microplate readers (MR) are laboratory instruments used for the measurement of analytes and monitoring the progression of biochemical reactions carried out in microplates.
Microplate readers (MR) are laboratory instruments used for the measurement of analytes and monitoring the progression of biochemical reactions carried out in microplates. These instruments form an integral part of routine laboratory procedures as they can be used for the quantification of parameters of interest, determination of cell viability and gene expression, and for various other applications in life sciences.
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Commercially available products include single-mode or multi-mode readers. Single-mode readers are preferred for basic applications, with the most commonly used read modes including fluorescence, absorbance, and luminescence. However, demand for multi-mode readers is gaining impetus due to the greater flexibility, cost efficiency, and compact sizing options offered by them. Moreover, in addition to fluorescence, absorbance, and luminescence capabilities, multi-mode readers currently offer several configurable modes for fluorescence polarization, fluorescence resonance energy transfer, time-resolved fluorescence, and amplified luminescent proximity homogeneous assays, among others. These capabilities are strengthening the growth prospects for multi-mode readers in the near future.
High-throughput screening using MR can minimize the operational time required and save reagent costs by enabling analysis of up to 3456 samples at a time. This allows for greater flexibility with sample handling and provides more time for data analysis and interpretation, which form an important aspect of research activities. Hence, research applications of these instruments are expected to rise, as evident by the launch of new products suitable for research laboratories. For instance, in April 2022, Molecular Devices, LLC (Danaher Corporation) launched its SpectraMax Mini Multi-Mode Reader with a compact and economical benchtop design ideal for academic laboratories. Similarly, in February 2022, BMG LABTECH launched the VANTAstar microplate reader suitable for use in life sciences research activities.
Microplate readers have been segmented on the basis of the following applications:
- Genomics and Proteomics Research
- Drug Discovery
- Clinical Diagnostics
- Other Applications
Genomics and proteomics research applications of MR are driven by the availability of a variety of reagent kits and microplate assays for protein library screening and assessment of cell viability. Similarly, drug discovery applications are fueled by the high throughput screening capabilities of the instrument, while clinical diagnostic use is gaining traction due to the increasing use of enzyme-linked immunosorbent assays. Other applications such as monitoring microbial growth and enzyme activities for bioprocess operations are anticipated to grow due to a rapid increase in bio-manufacturing processes in recent years.
Key Players
- Danaher Corporation
- Thermo Fisher Scientific, Inc.
- BMG Labtech
- PerkinElmer, Inc.
- Promega Corporation
- Bio-Rad Laboratories
- Lonza
- Agilent Technologies Inc.
- Enzo Life Sciences
Market Segmentation
- By Product
- Single-Mode Readers
- Absorbance Microplate Readers
- Fluorescence Microplate Readers
- Luminescence Microplate Readers
- Multi-Mode Readers
- Filter-based Microplate Readers
- Monochromator-based Microplate Readers
- Hybrid Microplate Readers
- Single-Mode Readers
- By Application
- Genomics and Proteomics Research
- Drug Discovery
- Clinical Diagnostics
- Other Applications
- By End-user
- Hospitals and Clinical Laboratories
- Pharmaceutical & Biotechnology Companies
- Academic & Research Institutions
- Others
- By Region
- North America
- Europe
- Asia Pacific
- Latin America
- Middle East & Africa
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