Mozart Therapeutics, Inc. today announced a $55 Million Series A Financing led by seed and Series A investor ARCH Venture Partners
- Advancing First-In-Class CD8 Treg Modulators to Restore Immune Balance SEATTLE, Oct. 26, 2021 /PRNewswire/ -- Mozart Therapeutics, Inc., a new biopharmaceutical company targeting a novel immune pathway to change the course of autoimmune and inflammatory disease, today announced a $55 Million Series A Financing led by seed and Series A investor ARCH Venture Partners along with Sofinnova Partners. Additional investors include Eli Lilly & Company, MRL Ventures Fund (the early-stage therapeutics-focused fund of Merck & Co., Inc.), Leaps by Bayer, Altitude Life Science Ventures, Alexandria Venture Investments. Mozart was founded on the seminal work of Mark M. Davis, PhD, a leading world expert in the field of T cell biology. Professor Davis discovered that a CD8 T regulatory cell network plays a key role in surveillance, recognition and elimination of inappropriately activated autoreactive and pathogenic immune cells that are a root cause for autoimmune and inflammatory disease1. The technology was licensed to Mozart to develop therapeutic candidates that target and modulate this network for the treatment of autoimmune and inflammatory disease. The company will use the Series A funds to progress its lead CD8 Treg Modulator into the clinic while also advancing additional programs generated from its novel platform. “Mozart is doing something truly unique to change the treatment paradigm for patients with autoimmune and inflammatory diseases. We aim to reset and restore the immune system balance by leveraging a novel pathway to develop first-in-class CD8 Treg modulators as disease-modifying therapeutics to address an unmet need across a spectrum of diseases.” said Katie Fanning, CEO of Mozart Therapeutics and a 35-year biotech industry veteran. “I am grateful to have the financial support of a strong syndicate of top tier healthcare investors who bring exceptional industry and strategic guidance to advance our therapeutic candidates through development and into the clinic.” “Modulating the CD8 T reg network represents a novel way to tackle a root cause of immune system dysregulation. We are pleased to support the advancement of Mozart’s innovative research that may hold promise to significantly impact the course of a wide range of diseases,” said Steve Gillis, PhD, Managing Director of ARCH Venture Partners and Chairman of the Mozart Board of Directors. “Given the significant and expansive need for impactful therapies for autoimmune and inflammatory disease it is exciting to see Mozart’s novel and distinct approach to address this challenge,” said Henrijette Richter, Managing Partner at Sofinnova Partners. “We are delighted to join this world-class syndicate of investors and look forward to supporting the team to establish Mozart as a world class leader in CD8 T regulatory cell network modulation.” Mozart also announced the formation of a scientific advisory board (SAB) composed of pre-eminent key opinion leaders in the fields of immunology, T cell biology, immune modulation and protein engineering. and its Board of Directors, composed of prominent biotechnology investment and pharmaceutical industry veterans. Mozart’s Scientific Advisory Board:
Mozart’s Board of Directors:
About CD8 Treg Modulators About Mozart Therapeutics 1Saligrama N, Davis MM et al., Nature 2019: https://doi.org/10.1038/s41586-019-1467-x Media Contact:
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