Medical News Today -- The National Institute for Health and Clinical Excellence (NICE) has published final guidance recommending the use of prasugrel in combination with aspirin as an option for preventing blood clots in the arteries of people with acute coronary syndromes. Acute coronary syndromes refers to a group of heart problems which occur due to narrowed coronary arteries. These heart problems cause chest pain, and specific types of heart attack. Prasugrel is a drug that can reduce or prevent the formation of blood clots in arteries by reducing the clumping together of platelets in the blood.