The global DNA synthesis market size was calculated at USD 4.97 billion in 2024 and is predicted to surpass around USD 29.98 billion by 2034 with a solid CAGR of 19.73% from 2025 to 2034.
In terms of revenue, the worldwide DNA synthesis market has been evaluated at USD 5.93 billion in 2025. The market expands because of innovations in biotechnology and increasing demand for personalized medicine, gene therapies, and diagnostics.
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DNA Synthesis Market Key Points
• North America generated more than 40% of revenue share in 2024.
• The oligonucleotide synthesis segment captured the maximum market share of around 39.98% in 2024.
• The research and development (R&D) contributed the highest market share of around 44.96% in 2024.
• The biopharmaceutical companies segment captured the biggest market share of 42.03% in 2024.
DNA Synthesis Market Revenue Analysis:
DNA Synthesis Market Revenue, by Service, 2022-2024 (USD Million)
|
Service |
2022 |
2023 |
2024 |
|
Oligonucleotide Synthesis |
1,371.2 |
1,649.8 |
1,986.4 |
|
Gene Synthesis |
2,128.8 |
2,518.7 |
2,982.5 |
DNA Synthesis Market Revenue, by
Application, 2022-2024 (USD Million) Application 2022 2023 2024 Research & Development 1,584.3 1,880.5 2,234.0 Therapeutics 1,216.8 1,453.3 1,737.3 Diagnostics 698.9 834.6 997.5 Market Overview and Industry Potential DNA synthesis is the artificial generation
of deoxyribonucleic acid (DNA). It includes several types of synthetic DNA,
including oligonucleotides, genes, and DNA fragments, tailored to meet customer
needs. Synthetic DNA plays a vital role in developing new drugs, vaccines, and
therapies for genetic disorders via gene modification and molecular
diagnostics. These diagnostics utilize PCR assays and nucleic acid-based
sensors to detect pathogens and diseases. The rising prevalence of chronic diseases
and mounting healthcare expenses have encouraged the adoption of synthetic DNA
by medical professionals due to personalization preferences. Synthetic DNA
markets experience continuous growth because scientists require increasing
numbers of innovative therapeutic drugs alongside new diagnostic devices and
various field research projects. The DNA synthesis market demonstrates great
potential to define the future trajectory of genomic and molecular biological
research as both the healthcare and biotechnology
fields expand. Artificial Integration (AI) in DNA Synthesis The DNA synthesis market utilizes artificial integration,
which means advanced technologies such as artificial intelligence, machine learning (ML), robotics, and
automation improve DNA synthesis processes. AI and ML systems optimize DNA
production protocols while forecasting results and identifying errors to
strengthen the accuracy and efficiency of DNA synthesis. This technology
enables mass production of DNA at high speed, and it serves as an essential
requirement for genomic applications, synthetic biological applications, and
personalized medical needs. Research and development speed up through system
integrations to enable quicker enhancements of gene therapies, diagnostic tools,
and genetic engineering applications. • In October 2024, the company Absci
Corporation, a data-first generative AI drug creation company, partnered with
Twist Bioscience Corporation, the synthetic DNA manufacturer, using its silicon
platform to develop a new therapeutic through the use of generative AI. Set up a meeting
at your convenience to get more insights instantly! https://www.precedenceresearch.com/schedule-meeting Major Trends in the DNA Synthesis Market Advancements in Genetic Engineering
Technologies The market demand for DNA synthesis
originates from ongoing progress in genetic engineering technology
developments. The market demand for custom DNA sequences grew exponentially
after the introduction of CRISPR-Cas9 and additional gene-editing innovations
which led to service market expansion. Research laboratories and biotechnology
companies need specialized DNA constructs for their operations; thus, DNA
synthesis stands crucial for implementing advanced genetic engineering
research. High Prevalence of Chronic Diseases Synthetic DNA products and services
experience increased usage and production because health conditions are
becoming more common, and people understand better how personalized
medicine works throughout the world. The rising number of cases demands
accurate early diagnosis techniques, which increased market demand for
synthetic DNA services and products. Rising Demand for Personalized Medicines Treatments and personalized medicine
deliver unique treatment options that use genetic information about each
individual. The scientific field integrates knowledge from pharmacogenomics
and pharmacogenetics as well as pharmacometabolomics and pharmacoproteomics.
The goal of targeted medicine is to enhance healthcare results through better
methods of early detection and prevention and therapy monitoring systems. Rising Use in Agriculture and Food
Industry The production of genetically modified (GM)
crops depends on DNA synthesis to add beneficial characteristics. Plant genomes
receive genetically modified DNA sequences that scientists synthesize for
creating crops with precise genetic changes. DNA technology enables scientists
to monitor gene expression modifications, thus supporting the management of
crop development and growth regulation. View Full Report@ https://www.precedenceresearch.com/dna-synthesis-market DNA Synthesis Market Report Coverage Report Coverage Details Market Size in 2025 USD 5.93 Billion Market Size by 2034 USD 29.98 Billion CAGR from 2025 to 2034 CAGR of 19.73% Dominating Region North America Base Year 2024 Forecast Period 2025 to 2034 Segments Covered Service, Application, End-User and
Regions Regions Covered North America, Europe, Asia-Pacific,
Latin America, and Middle East & Africa
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| +1 804 441 9344 DNA Synthesis Market Regional Outlook: U.S. DNA Synthesis Market Size to
Achieve USD 9.30 Bn by 2034 The U.S. DNA synthesis market size is
estimated at USD 1.90 billion in 2025 and is projected to achieve USD 9.30
billion by 2034, expanding at a solid CAGR of 19.10% from 2025 to 2034. North America dominated the global DNA
synthesis market in 2024. The development of these drugs continues to
accelerate as people become more aware of personalized treatments and the
growing number of chronic and genetic diseases. The market receives support
from key research institutions and universities, as well as biotech companies
that operate throughout this region. North American synthetic gene demand
experiences exponential growth because pharmaceutical organizations continuously
require fresh drug products, biological substances, and vaccine
developments. • The
American Cancer Society, Inc. predicts that 2,001,140 new cancer cases will
appear in the U.S. during 2024 based on their data. The growing number of cases
necessitates prompt, accurate diagnostic methods, which drives market adoption
of these services and products. Asia Pacific is expected to witness
lucrative growth in the DNA synthesis market during the forecast period. The
regional growth will be propelled by increasing investments made to construct
new DNA manufacturing facilities and expanding healthcare infrastructure drives
the regional growth. A growing demand for synthetic DNA exists because
researchers and diagnosticians need it to identify diseases effectively, while
personal medicine requirements also expand. Chinese pharmaceutical and
biotechnology firms adopt contract research organization services. • In May 2023,
GenScript unveiled the expansion of its oligonucleotide manufacturing facility in Jiangsu, China. DNA Synthesis Market Segmentation
Analysis Service Analysis The oligonucleotide synthesis segment
dominated the market with the largest share in 2024. The segment expansion occurs
because synthetic oligos gain popularity in molecular diagnostics, therapeutic
applications, and gene therapy developments. The fields of molecular biology,
genetics, and genomics rely on oligonucleotides to perform functions during PCR
DNA sequencing and gene expression experiments. The expanding knowledge of
genetic disorders drives up the requirement for oligonucleotide applications in
diagnosis and treatment development. The gene synthesis segment is anticipated
to grow rapidly over the forecast period. The process of gene synthesis builds
DNA sequences from scratch to design customized genes. Market expansion occurs
because of technological developments in gene synthesis systems with increasing
project complexity in genetic engineering applications. Through gene synthesis,
research institutions and industries can create DNA sequences that meet their
precise requirements. Market expansion will be driven by the ongoing strategic
gene synthesis service launches of key market participants to ensure customer
demand satisfaction during the forecast period. • In November 2023,
Twist Bioscience launched its new product, Twist Express Genes, which provides
gene synthesis service for genes between 0.3 to 5.0kb and delivers the
synthesized genes within five to seven business days. Application Analysis The research and development segment held
the largest share of the DNA synthesis market. R&D demand is particularly
high for DNA synthesis applications in molecular biology, genetic testing, and
drug discovery. DNA synthesis benefits increasingly from the adoption of CRISPR
technology, which extends its use in genetic engineering and therapeutic
research needs. The intense research expansion results from affordable DNA
synthesis service availability which helps researchers accomplish genetics and
drug discovery studies at unprecedented speed and accuracy. The therapeutics segment is expected to
witness a notable growth rate during the forecast period. DNA synthesis plays a
vital role in building disease-specific treatments for different genetic
disorders and cancers, as well as providing DNA sequencing options and
therapeutic enzyme
analysis tools. The rising priority of precision
medicine, as well as personalized healthcare development, supports
synthetic DNA’s dominant role. DNA synthesis provides an essential tool to
create exclusive DNA sequences needed for medical applications, including
vaccine development and gene therapy,
as well as drug-protein manufacturing. • In
April 2024, the U.S. Food and Drug Administration
issued Pfizer Inc. approval to market BEQVEZ as an adeno-associated virus
(AAV)-based gene therapy that treats adult patients suffering from moderate to
severe hemophilia B. End-User Analysis The biopharmaceutical
companies segment accounted for the largest market share in 2024. The segment
expands due to the heightened usage of synthesized DNA products within
pharmaceutical and biotechnological companies, which allows these firms to
create new disease treatment options, thus growing the market. DNA synthesis plays a fundamental role in
the development of biopharmaceutical products, which include therapeutic
proteins, vaccines, and gene therapies. Biopharmaceutical enterprises use
synthetic DNA to create new medical treatments for cancer, genetic disorders,
and autoimmune conditions because of expanding demands for precise medicinal
interventions. • In
January 2024, the U.S. Food and Drug Administration
granted Vertex Pharmaceuticals, alongside CRISPR Therapeutics, approval to
treat sickle cell disease through their gene therapy. The academic and research institutes
segment is expected to show the fastest growth during the forecast period.
Academic Research Institutes utilize DNA synthesis for their research
activities dedicated to synthetic biology genetics editing and genomics
projects. Modern research heavily relies on Strategic DNA synthesis since it
enables synthetic genetic development along with genetic modification abilities
to produce DNA libraries for various research applications. Academic
establishments require DNA synthesis solutions because these institutions
continue to expand their genomics and
biotechnology research activities. Browse More Insights: 🔸DNA Synthesizer Market: https://www.precedenceresearch.com/dna-synthesizer-market 🔸Gene Synthesis Market: https://www.precedenceresearch.com/gene-synthesis-market 🔸DNA Polymerase Market: https://www.precedenceresearch.com/dna-polymerase-market 🔸DNA Nanotechnology Market: https://www.precedenceresearch.com/dna-nanotechnology-market 🔸Synthetic Biology Market: https://www.precedenceresearch.com/synthetic-biology-market 🔸DNA Sequencing Market: https://www.precedenceresearch.com/dna-sequencing-market 🔸DNA Microarray Market: https://www.precedenceresearch.com/dna-microarray-market 🔸gRNA Market: https://www.precedenceresearch.com/grna-market 🔸Molecular Biology Enzymes Market: https://www.precedenceresearch.com/molecular-biology-enzymes-market 🔸Gene Editing Market: https://www.precedenceresearch.com/gene-editing-market DNA Synthesis Market Top Companies • LGC Biosearch Technologie • Bioneer Corporation • Thermo Fisher Scientific, Inc. • IBA GmbH • Twist Bioscience • Eton Bioscience • Quintara Biosciences • Eurofins Scientific • Integrated DNA Technologies, Inc • GenScript Biotech Corporation What is Going Around the Globe? • In May 2024, Molecular Assemblies, Inc. introduced its Full Enzymatic Synthesis
(FES) technology licensing platform through the Partnering Program for chosen
business partners. Members of the program gain access to synthesis automation
equipment and licenses, which enable them to conduct research within their
facilities. • In March 2024, Elegen announced the commercial launch of an enhancement to
ENFINIA DNA that provides researchers with a reliable supply of very
high-complexity DNA in as fast as 10 business days. This upgrade to ENFINIA DNA
sets a new standard for DNA manufacturing, providing an industry-leading
combination of speed, length, NGS-verified accuracy, and complexity. • In May 2023, NA Script, the Enzymatic DNA Synthesis (EDS) technology worldwide
leader, released its SYNTAX DNA printing platform with an STX-200 automated
system and the latest biochemistry solutions and software updates for broad
commercial use. Segments Covered in the Report By Service • Oligonucleotide
Synthesis o Custom Oligonucleotide Synthesis o
Pre-designed Oligonucleotide Synthesis • Gene
Synthesis By Application • Research
and Development • Therapeutics • Diagnostic By End-User • Biopharmaceutical
Companies • Academic
and Research Institutes • Contract
Research Organizations By Region • North
America • Europe • Asia
Pacific • Latin
America • Middle
East and Africa Immediate
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