Roche Applied Science Makes Exome Sequencing a Reality, a Giant Step Towards Personalized Medicine

MADISON, Wis. & BRANFORD, Conn.--(BUSINESS WIRE)--A key milestone for personalized medicine has been achieved by two Roche Applied Science companies, Roche NimbleGen and 454 Life Sciences, in developing revolutionary technologies to resequence all human exons from individual genomes. Roche NimbleGen has launched Sequence Capture 2.1M Human Exome microarrays, built on the HD2 platform, which allows researchers to capture all exons in the genome (i.e. the exome) on a single array with 2.1 million long oligonucleotide probes. Coupled with the Genome Sequencer FLX system from 454 Life Sciences, researchers worldwide now have the capability to assess genetic variation within the exome of any individual.
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