Sanger sequencing is one of the oldest DNA sequencing methods carried out using oligonucleotide primers and chain termination.
Market Dynamics:
Sanger sequencing is one of the oldest DNA sequencing methods carried out using oligonucleotide primers and chain termination. It is commonly used for sequencing plasmid DNA, Polymerase Chain Reaction (PCR) products, and Bacterial Artificial Chromosomes (BAC) and is the most preferred choice for mutation detection. It is a cost-effective and highly accurate method for analyzing small DNA regions within limited number of samples. In Sanger sequencing, a DNA primer that is complementary to the template DNA is used as a starting point for DNA synthesis. This technique has an advantage over other short-read sequencing as it can produce DNA sequences shorter than 500 nucleotides. Many companies offer a wide range of Sanger sequencing services and advanced assay kits for primer walking, PCR purification, direct colony sequencing, or complex template sequencing for simplifying workflow, reducing turnaround times, and obtaining high-quality results.
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Factors such as increasing focus on developing advanced and effective drugs, high prevalence of rare genetic diseases, and high preference for Sanger sequencing in clinical diagnosis are expected to drive global market revenue growth. Ongoing research on genomics and proteomics and increasing investments in R&D activities are also expected to fuel Sanger Sequencing Services market growth going ahead. However, shortage of skilled healthcare professionals, inaccessibility to advanced assay kits, and lack of standardized protocols for sequencing methods are some key factors that can hamper Sanger Sequencing Services market growth to a certain extent during the forecast period.
COVID-19 Impact Analysis
- Social distancing and restrictions severely disrupted businesses and operations
- Lockdowns caused disruptions in transportation and logistics
- Impacted manufacturing activities and mining operations globally
- Took a toll on economy of various countries
- Caused sudden and drastic downturn in economic activity
- Disrupted agriculture, fisheries, dairy, and other sectors
- Caused loss of employment and financial crisis
- Supply impacts were further compounded owing to reduced disposable income
- Emergence of variants continue to cause concerns and impact normal routines
Biomarkers & Cancer to Account for Significantly Larger Revenue Share:
The biomarkers and cancer segment is expected to account for a significantly larger revenue share during the forecast period owing to rising incidence of various types of cancers, high demand for advanced Sanger sequencing systems and services for identifying cancer biomarkers, and increasing investments for ongoing cancer research.
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Pharmaceutical and Biotechnology Companies Segment To Register Rapid Revenue CAGR:
The pharmaceutical and biotechnology companies segment is expected to register rapid revenue CAGR between 2021 and 2028. Revenue growth can be attributed to factors such as increasing prevalence of cancer and rare genetic disorders across the globe, rapid adoption of Sanger sequencing services by pharmaceutical and biotechnology companies to identify genetic variations and mutations, rising research-based activities on genome mapping, and high focus on novel drug development.
North America to Lead in Terms of Revenue Share:
North America is expected to account for largest revenue share in the global market during the forecast period owing to factors such as increasing prevalence of cancer and genetic diseases, rapid advancements in sequencing techniques, and growing awareness about Sanger sequencing. Other factors such as ongoing research on molecular biology and genomics, presence of leading players, and increasing investments in developing advanced products and services are expected to drive North America market growth during the forecast period.
Major Companies in the Market Include:
- Source BioScience
- GenScript Biotech Corporation
- Thermo Fisher Scientific, Inc.
- LGC Science Group Limited
- Fasteris SA
- CeMIA SA
- Quintara Biosciences
- GenHunter Corporation
- GENEWIZ
- Nucleics
- SciGenom Labs Pvt. Limited,
- Microsynth AG. Inc.
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For the purpose of this report, Emergen Research has segmented the global Sanger sequencing services market on the basis of application, end use and region:
Application Outlook (Revenue, USD Billion; 2018–2028)
- Diagnostics
- Biomarkers & Cancer
- Reproductive Health
- Personalized Medicine
- Forensics
- Others
End Use Outlook (Revenue, USD Billion; 2018–2028)
- Academic & Research Institutes
- Pharmaceutical & Biotechnology Companies
- Hospitals & Clinics
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Regional Outlook (Revenue, USD Billion; 2018–2028)
- North America
- U.S.
- Canada
- Mexico
- Europe
- Germany
- France
- U.K.
- BENELUX
- Italy
- Rest of Europe
- Asia Pacific
- China
- India
- Japan
- South Korea
- Rest of APAC
- Latin America
- Brazil
- Rest of LATAM
- Middle East & Africa
- Saudi Arabia
- U.A.E.
- South Africa
- Turkey
- Rest of MEA
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