Sublingual Zolpidem for Middle-of-the-Night Awakening Does Not Induce Tolerance, Rebound, or Increased Use

EGMN -- A sublingual 3.5-mg formulation of zolpidem tartrate is effective for middle-of-the-night insomnia, producing no tolerance, rebound, or increase in use over 4 weeks, investigators reported at the congress of the European College of Neuropsychopharmacology.