Tangential Flow Filtration Market Size, Share | Report 2022-2030

According to Vision Research Reports, the global tangential flow filtration market size was estimated at around USD 1.2 billion in 2021 and it is projected to hit around USD 3.69 billion by 2030, growing at a CAGR of 13.3% from 2022 to 2030.

Tangential flow filtration (TFF) is one of the operating modes of the ultrafiltration technique in which the molecules are separated based on their size and purify them. For this purpose, a porous polymeric membrane is used. It is used to desalinize and concentrate the sample of size 10ml-1000l (volume solution) in the downstream process. Tangential flow filtration (TFF) has wide application in various biological fields like biochemistry, immunology, molecular biology, microbiology, protein chemistry. Along with filtration, TFF is also used to remove cell scrap or waste from the culture broth.

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Following are the advantages of tangential flow filtration (TFF) –

• Easy to use and simple set up the system.
• Processing is fast and efficient.
• Time-saving as two steps are performed in the same system (desalt and concentrate the sample).
• Scale up and scale-down processes can be performed.
• Safe and reusable.
• Cost saving and higher productivity.

Scope of The Report

The COVID-19 pandemic has driven the tangential flow filtration (TFF) market due to the rise in downstream processes for vaccine production which thoroughly requires purification and filtration techniques. The investments from the public and private sector in the upstream and downstream process has also paved the way for the growth of the TFF markets. To expand the filtration division of Parker Bioscience, Parker Hannifin U.S. has joined the alliance with Bioflex Solution U.S. Moreover, an increase in the government funds in the advancements of research and development, biotechnology sector, and improvement in the healthcare sector has a huge positive impact on the market growth.

Along with this the labor cost for the system is also low with eventually drives the market. Recently, Repligen Corporation patented for TFDF system (tangential flow depth filtration) with the promising results of decreased fouling and better filter flux capacity. Therapeutic drug production and recombinant protein production by the pharmaceutical industries has been increased in recent times. For this TFF products has a greater application propelling the growth of the market. PELLICON SINGLE-PASS TFF is one of the devices for filtration of the feed process.

The market is segmented by type, material, technology, application, end-user and region. Considering the regional analysis, North America, and Europe holds the major market share as they have major biopharmaceutical and biotechnological industry setups. Asia Pacific market is also expected to flourish in the coming years due to the growing preponderance to viral diseases, advancements in R&D projects, improvements in the generic and healthcare infrastructure. Currently, China leads the Asia-Pacific market growth. India is the third leading country having major biotechnology companies and also the startup companies for bioprocessing applications.

Key Market Trends

Single-use TFF Systems Segment Captures the Largest Market Share and is Expected to Retain its Dominance over the Forecast Period

The rise in the adoption of single-use technologies can be attributed to the benefits associated with them, such as reduced cross-contamination, increased flexibility, and decreased process time. This, in turn, increases the adoption of single-use TFF systems across the world. These fully automated single-use systems have various benefits, such as reduced validation, lower capital costs, and decreased cleaning requirements. In addition, with increasing technological advancements in single-use TFF, the biologics manufacturing landscape is expected to reshape itself, to facilitate the industry to adopt simpler, disposable, single-use systems.

Key Players

• Sartorius AG
• Sterlitech Corporation
• Repligen Corporation
• Synder Filtration, Inc.
• Novasep
• Micro Filt India Pvt. Ltd.
• BIONET
• Alfa Laval AB
• Merck KGTaA
• Danaher Corporation
• GE Healthcare
• Parker Hannifin Corporation
• Spf Technologies, LLC 
• ANDRITZ
• Solaris Biotechnology Srl., 
• Koch Membrane System Inc.
• Stedim Biotech and SYSBIOTECH GmbH
• others

Market Segmentation

• By Type
  • Single-Use Tangential Flow Filtration Systems
  • Reusable Tangential Flow Filtration Systems
  • Membrane Filters (Cassettes, Capsules & Cartridges)
  • Automated Systems
  • Filtration Accessories
• By Material
  • Polyethersulfone
  • Polyvinylidene Difluoride
  • Nylon
  • Polyetrafluoroethylene
  • Mixed Cellulose Ester & Cellulose Acetate
  • Polycarbonate Tracked Etched
  • Regenerated Cellulose
  • Other materials
• By Technology
  • Ultrafiltration
  • Microfiltration
  • Nano Filtration
  • Reverse Osmosis
• By Application
  • Final Product processing
    • API Filtration
    • Protein purification
    • Vaccine and antibody processing
    • Others
  • Raw material filtration
    • Media and buffer filtration
    • prefiltration
    • bioburden testing
  • Pharmaceutical Water Production
  • Cell Separation
  • Air Purification
• By End user
  • Pharmaceutical and Biotechnology Companies
  • CMOs & CROs
  • Academic Institutes and Research Laboratories
• By Region
  • North America
  • Europe 
  • Asia-Pacific
  • Latin America
  • Middle East And Africa

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