Investor Reception to be Held on Monday December 7, 2015 from 7:45 pm - 9:00 pm ET at the Hyatt Regency Orlando With Presentations by Leading Clinical Investigators
ORLANDO, Fla., Dec. 04, 2015 (GLOBE NEWSWIRE) -- TG Therapeutics, Inc. (Nasdaq:TGTX) today recapped the schedule of data presentations for their lead compounds at the upcoming 57th American Society of Hematology Annual Meeting (ASH), to be held December 5-8, 2015, at the Orange County Convention Center in Orlando, Florida.
Presentations on TG-1101 and TGR-1202 at the ASH meeting include the following:
Clinical Posters:
• Title: Ublituximab + TGR-1202 Demonstrates Activity and Favorable Safety Profile in Relapsed/Refractory B-Cell NHL and High-Risk CLL: Phase I Results
o Abstract Number: 1538
o Session: 624. Lymphoma: Therapy with Biologic Agents, excluding Pre-Clinical Models: Poster I
o Date and Time: Saturday, December 5, 2015; 5:30 PM- 7:30 PM ET
o Location: Orange County Convention Center, Hall A
o Presenter: Matthew Lunning, DO
• Title: A Phase I Trial of TGR-1202, a Next Generation Once Daily PI3K-Delta Inhibitor in Combination with Obinutuzumab Plus Chlorambucil, in Patients with Chronic Lymphocytic Leukemia
o Abstract Number: 2942
o Session: 642. CLL: Therapy, excluding Transplantation: Poster II
o Date and Time: Sunday, December 6, 2015; 6:00 PM-8:00 PM ET
o Location: Orange County Convention Center, Hall A
o Presenter: Daruka Mahadevan, MD, PhD
• Title: Ublituximab (TG-1101), A Novel Glycoengineered Anti-CD20 Monoclonal Antibody, in Combination With Ibrutinib is Highly Active in Patients With Relapsed And/Or Refractory Mantle Cell Lymphoma; Results of a Phase II Trial
o Abstract Number: 3980
o Session: 624. Lymphoma: Therapy with Biologic Agents, excluding Pre-Clinical Models: Poster III
o Date and Time: Monday, December 7, 2015; 6:00 PM- 8:00 PM ET
o Location: Orange County Convention Center, Hall A
o Presenter: Kathryn Kolibaba, MD
• Title: TGR-1202, a Novel Once Daily PI3K-Delta Inhibitor, Demonstrates Clinical Activity with a Favorable Safety Profile in Patients with CLL and B-Cell Lymphoma
o Abstract Number: 4154
o Session: 642. CLL: Therapy, excluding Transplantation: Poster III
o Date and Time: Monday, December 7, 2015; 6:00 PM- 8:00 PM ET
o Location: Orange County Convention Center, Hall A
o Presenter: Owen O'Connor, MD, PhD
Non-Clinical Oral Presentation:
• Title: Disruption of the mTOR-eIF4F Axis By Selectively Targeting PI3Kdelta and Proteasome Potently Inhibits Cap Dependent Translation of c-Myc in Aggressive Lymphomas
o Abstract Number: 593
o Oral Session: 625. Lymphoma: Pre-Clinical – Chemotherapy and Biologic Agents: Novel Therapies and Targets in Lymphoma
o Date and Time: Monday, December 7, 2015; 10:30 AM - 12:00 PM ET
o Presentation Time: 11:30 AM ET
o Location: Orange County Convention Center, Tangerine 1 (WF1)
o Presenter: Changchun Deng, MD, PhD
A copy of the above referenced abstracts can be viewed online through the ASH meeting website at www.hematology.org.
TG Therapeutics will also host a reception on Monday, December 7th, 2015 beginning at 7:45pm ET, with featured presentations beginning promptly at 8:00pm ET. The event will take place at the Hyatt Regency Orlando in the Bayhill 17/18 Room. This event will be webcast live and will be available on the Events page, located within the Investors & Media section of the Company’s website at www.tgtherapeutics.com, as well as archived for future review. This event will also be broadcast via conference call. In order to access the conference line, please call 1-877-407-8029 (U.S.), 1-201-689-8029 (outside the U.S.), and reference Conference Title: TG Therapeutics 2015 Investor & Analyst Event. ABOUT TG THERAPEUTICS, INC.
TG Therapeutics is a biopharmaceutical company focused on the acquisition, development and commercialization of novel treatments for B-cell malignancies and autoimmune diseases. Currently, the Company is developing two therapies targeting hematological malignancies. TG-1101 (ublituximab) is a novel, glycoengineered monoclonal antibody that targets a specific and unique epitope on the CD20 antigen found on mature B-lymphocytes. TG Therapeutics is also developing TGR-1202, an orally available PI3K delta inhibitor. The delta isoform of PI3K is strongly expressed in cells of hematopoietic origin and is believed to be important in the proliferation and survival of B-lymphocytes. Both TG-1101 and TGR-1202 are in clinical development for patients with hematologic malignancies. The Company also has a pre-clinical program to develop IRAK4 inhibitors, as well as an antibody research program to develop anti-PD-L1 and anti-GITR antibodies. TG Therapeutics is headquartered in New York City.
ORLANDO, Fla., Dec. 04, 2015 (GLOBE NEWSWIRE) -- TG Therapeutics, Inc. (Nasdaq:TGTX) today recapped the schedule of data presentations for their lead compounds at the upcoming 57th American Society of Hematology Annual Meeting (ASH), to be held December 5-8, 2015, at the Orange County Convention Center in Orlando, Florida.
Presentations on TG-1101 and TGR-1202 at the ASH meeting include the following:
Clinical Posters:
• Title: Ublituximab + TGR-1202 Demonstrates Activity and Favorable Safety Profile in Relapsed/Refractory B-Cell NHL and High-Risk CLL: Phase I Results
o Abstract Number: 1538
o Session: 624. Lymphoma: Therapy with Biologic Agents, excluding Pre-Clinical Models: Poster I
o Date and Time: Saturday, December 5, 2015; 5:30 PM- 7:30 PM ET
o Location: Orange County Convention Center, Hall A
o Presenter: Matthew Lunning, DO
• Title: A Phase I Trial of TGR-1202, a Next Generation Once Daily PI3K-Delta Inhibitor in Combination with Obinutuzumab Plus Chlorambucil, in Patients with Chronic Lymphocytic Leukemia
o Abstract Number: 2942
o Session: 642. CLL: Therapy, excluding Transplantation: Poster II
o Date and Time: Sunday, December 6, 2015; 6:00 PM-8:00 PM ET
o Location: Orange County Convention Center, Hall A
o Presenter: Daruka Mahadevan, MD, PhD
• Title: Ublituximab (TG-1101), A Novel Glycoengineered Anti-CD20 Monoclonal Antibody, in Combination With Ibrutinib is Highly Active in Patients With Relapsed And/Or Refractory Mantle Cell Lymphoma; Results of a Phase II Trial
o Abstract Number: 3980
o Session: 624. Lymphoma: Therapy with Biologic Agents, excluding Pre-Clinical Models: Poster III
o Date and Time: Monday, December 7, 2015; 6:00 PM- 8:00 PM ET
o Location: Orange County Convention Center, Hall A
o Presenter: Kathryn Kolibaba, MD
• Title: TGR-1202, a Novel Once Daily PI3K-Delta Inhibitor, Demonstrates Clinical Activity with a Favorable Safety Profile in Patients with CLL and B-Cell Lymphoma
o Abstract Number: 4154
o Session: 642. CLL: Therapy, excluding Transplantation: Poster III
o Date and Time: Monday, December 7, 2015; 6:00 PM- 8:00 PM ET
o Location: Orange County Convention Center, Hall A
o Presenter: Owen O'Connor, MD, PhD
Non-Clinical Oral Presentation:
• Title: Disruption of the mTOR-eIF4F Axis By Selectively Targeting PI3Kdelta and Proteasome Potently Inhibits Cap Dependent Translation of c-Myc in Aggressive Lymphomas
o Abstract Number: 593
o Oral Session: 625. Lymphoma: Pre-Clinical – Chemotherapy and Biologic Agents: Novel Therapies and Targets in Lymphoma
o Date and Time: Monday, December 7, 2015; 10:30 AM - 12:00 PM ET
o Presentation Time: 11:30 AM ET
o Location: Orange County Convention Center, Tangerine 1 (WF1)
o Presenter: Changchun Deng, MD, PhD
A copy of the above referenced abstracts can be viewed online through the ASH meeting website at www.hematology.org.
TG Therapeutics will also host a reception on Monday, December 7th, 2015 beginning at 7:45pm ET, with featured presentations beginning promptly at 8:00pm ET. The event will take place at the Hyatt Regency Orlando in the Bayhill 17/18 Room. This event will be webcast live and will be available on the Events page, located within the Investors & Media section of the Company’s website at www.tgtherapeutics.com, as well as archived for future review. This event will also be broadcast via conference call. In order to access the conference line, please call 1-877-407-8029 (U.S.), 1-201-689-8029 (outside the U.S.), and reference Conference Title: TG Therapeutics 2015 Investor & Analyst Event. ABOUT TG THERAPEUTICS, INC.
TG Therapeutics is a biopharmaceutical company focused on the acquisition, development and commercialization of novel treatments for B-cell malignancies and autoimmune diseases. Currently, the Company is developing two therapies targeting hematological malignancies. TG-1101 (ublituximab) is a novel, glycoengineered monoclonal antibody that targets a specific and unique epitope on the CD20 antigen found on mature B-lymphocytes. TG Therapeutics is also developing TGR-1202, an orally available PI3K delta inhibitor. The delta isoform of PI3K is strongly expressed in cells of hematopoietic origin and is believed to be important in the proliferation and survival of B-lymphocytes. Both TG-1101 and TGR-1202 are in clinical development for patients with hematologic malignancies. The Company also has a pre-clinical program to develop IRAK4 inhibitors, as well as an antibody research program to develop anti-PD-L1 and anti-GITR antibodies. TG Therapeutics is headquartered in New York City.
